Double negative

However, the reason for the second statement is that the difficulty in proving that a sample came from a given population is easier to see if we reword the statement of it by making it a double negative, and ask whether we can prove that it did not come from a different population Now the nature of the difficulty becomes clearer we have no information about the nature of the different population that we want to test against. 

The advice here is simple Use of double negatives is unnecessary and redundant. Eliminate it from your writing. 

When you see a double negative, immediately change that double negative to one positive sign. For example, 6 - -8 simplifies to 6 + 8. 

Double negative (CD4-CD8-) TCR-ap-f Treg cells that mediate tolerance in several experimental autoimmune diseases have been described [ 111 ]. These double negative T cells are specific for MHC class I molecules and the suppressive effect of these cells on the proliferation and cytotoxic activity of CD8-I- T cells with the same antigen specificity was not mediated by cytokines, but instead was attributed to Fas-mediated apoptosis of alloreactive T cells [112]. 

StroberS,ChengL,ZengD,Palathu-mpat R, Dejbakhsh-Jones S, Huie P, et al Double negative (CD4-CD8- p+) T cells which promote tolerance induction and regulate autoimmunity. Immunol Rev 1996 149 217-230. 

Koelewijn-Strattner, G. J. (1990). Race, gender and the scientific professions Double negative or double jeopardy. Master s Thesis. University of Maryland, College Park. 

HI. Haas, J. P, Grunke, M., Frank, C., Kolowos, W., Dimecker, D., Leipold, G., Hieronymus, T., Lorenz, H. M., and Herrmann, M., Increased spontaneous in vitro apoptosis in double negative T cells of humans with a fas/apo-1 mutation. Cell Death Differ. 5,751-757 (1998). 

Using the notation of Kroger and Vink,3 the symbol Oi" denotes an interstitial oxygen ion carrying an effective double negative charge and h denotes an electron hole. 

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