Double bonds, overview nucleophiles

The inability of certain nucleophiles to add to the carbon-nitrogen double bond of iminesfimine derivatives, coupled with the propensity of basic reagents to preferentially abstract protons a to the imine double bond, has limited the utility of the group in synthetic organic chemistry. While unique solutions exist for individual reactions, they are at best only applicable to a particular structural class of azomethines. Since structurally diverse imine derivatives have been utilized for the preparation of highly functionalized amines, an overview of some of the structural features of azometiiines and nonstabilized... 

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