Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Dose-response relationships genetic determinants

Two types of dose-response relationships are observed. The first is the incremental change in response of a single system or individual as the dose is increased. The second is the distribution of reponses in a population of individuals given different doses of the agent. The former are frequently used for the determination of the mechanism of interaction between the chemical and the biological system. The latter describe the response of a population of individuals and can also be used to determine multimodal responses indicative of genetic variations. [Pg.37]

Hematology in human populations has a number of genetic determinants, and the genetic polymorphism for various components of human blood compartments has the potential to affect the binding of lead in blood, the subsequent dose—toxic response relationships for lead from such alterations, and to enhance the variability between subjects with the same overall external lead contact. [Pg.282]

See other pages where Dose-response relationships genetic determinants is mentioned: [Pg.88]    [Pg.463]    [Pg.4554]    [Pg.247]    [Pg.262]    [Pg.12]    [Pg.346]    [Pg.341]    [Pg.346]    [Pg.355]    [Pg.492]    [Pg.494]    [Pg.461]    [Pg.334]    [Pg.31]    [Pg.189]    [Pg.509]    [Pg.121]   
See also in sourсe #XX -- [ Pg.751 ]



SEARCH



Dose relationships

Dose-response relationship

Genetic determinism

Relationship determination

Response Relationship

Response determination

© 2024 chempedia.info