Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Glutethimide ‘Doriden

Nonbarbiturates. After the introduction of the barbiturates, there was little progress in the medical treatment of anxiety until meprobamate (Equanil, Miltown) was introduced in 1950. Soon after its introduction, a series of similar medicines entered the market, including carisoprodol (Soma), glutethimide (Doriden), methaqualone (Qaalude, Sopor), methyprylon (Noludar), and ethchlorvynol (Placidyl). These medications have all been used to treat anxiety, insomnia, and muscle spasms. [Pg.131]

Glutethimide (Doriden ) was introduced in 1954 as a substitute for barbiturates. Its street names include GB, glue, and goof-balls. The combination of glutethimide and codeine is called doors and 4s and pancakes and syrup. The combined euphoria resembles that of heroin, and effects can last for about eight hours. [Pg.82]

Secobarbital (Seconal) Diphenhydramine (Benadryl) Glutethimide (Doriden) Meprobamate (Miltown) Lidocaine (Xylocaine) Prominal (Mebaral)... [Pg.620]

Glutethimide (Doriden), a highly lipid-soluble drug classified as a sedative-hypnotic, was introduced in 1954 as a safe barbiturate substitute. However, its addiction potential and the severity of withdrawal symptoms were similar to those of barbiturates. In 1991, glutethimide was classified as a Schedule II controlled substance in response to an upsurge in the prevalence of diversion, abuse, and overdose deaths. The drug is illegal in the United States and in several other countries. It is classified as a sedative-hypnotic. [Pg.467]

Although some sedative-hypnotics such as the nonbarbiturates glutethimide (Doriden) and methaqualone (Quaalude) were once legally prescribed drugs, these substances were banned from use in the United States because of their potential for addiction and abuse. Some sedative-hypnotics such as flunitrazepam (Rohypnol) are illegal in the United States but are legal in Europe and Latin America. [Pg.472]

Glutethimide Doriden Dorrmide Ciba-Geigy Cenci (USA) Piperidinedione 1954 250600 p.o. [Pg.211]

W9. Winsten, 8., A simplified method for the analysis of glutethimide (Doriden) by gas liquid chromatography. Clin. Chem. 12, 536 (1966). [Pg.307]

Glutethimide (Doriden) is used to cause daytime or preoperative sedation, or for the treatment of simple insomnia. Furthermore, it is useful in patients who cannot tolerate barbiturates. [Pg.637]

Glutethimide. 3-Ethy 1.3-phenyl-2, 6-piperidinedi -one 2-elhyl-2-phenyIglutarimide a-ethyl-a-phenylglutar-imide 3-ethyl-3-phenyl-2,6-dioxopiperidine 3-ethyl-3-phetiy -2,6-diketopiperidine Elrodorm Doriden-Sed Dori-... [Pg.703]

When the free prescribing of barbiturates began to be denounced, manufacturers were quick to market similarly substituted piperidines (i.e. rings with one nitrogen atom instead of two) such as methyprylone ( Noludar ) and glutethimide ( Doriden ), without any notable gain in selectivity (Mautner and Clemson, 1970 Hansch /a/., 1968). [Pg.623]

Stillwell WG, Stafford M, Horning MG (1973) Metabolism of glutethimide (doriden) by the epoxide-diol pathway in the rat and guinea pig. Res Commun Chem Pathol Pharmacol 6 579-590... [Pg.74]

The Use of Hydrolytic Rate Constants to Study Glutethimide (Doriden) and Metabolite Concentrations in Human Blood... [Pg.154]

See other pages where Glutethimide ‘Doriden is mentioned: [Pg.1694]    [Pg.1694]    [Pg.105]    [Pg.235]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.105]    [Pg.235]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.1694]    [Pg.226]    [Pg.176]    [Pg.1415]    [Pg.181]    [Pg.115]    [Pg.462]    [Pg.466]    [Pg.492]    [Pg.581]    [Pg.169]    [Pg.132]    [Pg.134]    [Pg.110]    [Pg.2308]    [Pg.965]    [Pg.161]   


SEARCH



© 2024 chempedia.info