Dole, Vincent

The use of methadone maintenance for heroin addicts is developed by Rockefeller University researchers Vincent Dole and Marie Nyswander. 

Methadone began to be used as a treatment for heroin addiction in the 1960s. In 1963, Dr. Vincent Dole, an expert in metabolic disorders, and Dr. Marie Nyswander, a psychiatrist who had worked in the U.S. Public Health facility for heroin addicts in Lexington, Kentucky, began... 

Methadone maintenance treatment was established in 1964 in New York City by Vincent Dole and Marie Nyswander. In the initial studies, subjects who were heavily addicted to heroin were evaluated and stabilized on daily methadone doses as inpatients before transfer to an outpatient clinic for continued treatment. With further experience, it was feasible to drop the inpatient phase (65). 

Vincent Dole, professor emeritus at a symposium held at the Rockefeller Institute in 1985, commented on what he termed the "Classical Age" CL) ... 

Martinus N, Sinclair CD, Vincent CA (1977) The extended Jones-Dole equation. Electrochim Acta 22 1183-1187. doi 10.1016/0013-4686(77)80059-5... 

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