Diterpene methyl ester

R = Ac] and milliamine B [74 R = R = H, R = (75)] have been isolated. The structure of milliamine A rests on spectral evidence and hydrolysis with sodium methoxide in methanol to the diterpene (74 R = R = R = H) and the methyl ester corresponding to part structure (75). The structure of the diterpene tetraol, (74 R = R = r3 = H) had been previously determined by X-ray crystallographic analysis the structure of the alkaloidal portion was established by further degradation with hydrochloric acid to methyl anthranilate and compound (76), which was found to be identical with an authentic sample... 

Spiro diterpenes E. viscida, as the name implies, is a species whose branches and leaves carry a sticky resin and this appearance gave rise to the vernacular name of varnish bush. The resin consists largely of material extractable into base. The major components are two diterpene acids (131,132) which disclosed a new diterpene skeleton (111). Although a small amount of the crystalline dihydroxy acid (131) could be obtained after tedious separation, as often found with Eremophila resins, the process was simplified by methylation of the crude acidic fraction and separation of the methyl esters. 

DITERPENE EE-II (METHYL ESTER) Source Evemophila exotrachys Kraenzlin... 

Diterpene GC-XIb (methyl ester) (C21H32O3) 71 Diterpene SL-V (C2iH3203) 344 Epispongiadiol (C20H28O4) 416 Epoxivellozui (C20H28O4) 405... 

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