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Dissolution testing similarity factor

The most common approach for the comparison of dissolution profiles is model-independent approach using the similarity factor f2. The pre-requisites for using the /2-test are the following ... [Pg.335]

When comparing the test and reference products, dissolution profiles should be compared using a similarity factor (fz). The similarity factor is a logarithmic reciprocal square root transformation of the sum of squared error and is... [Pg.558]

The dissolution equivalence is tested using the statistical dissolution model, termed f2 or similarity factor, and is described by the equation... [Pg.963]


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See also in sourсe #XX -- [ Pg.255 ]




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Dissolution testing

Similarity factor

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