Dispiro pentadecanes

Wang et al. found in 2005 that the reaction of certain imines 422 with Meldrum s acid 112 led to significant amounts of a spirocyclic by-product 424, beneath the desired benzo[/]-quinolin-3-ones 423 (Scheme 13.87) [170]. Those findings encouraged Tu et al. to develop a three-component reaction selectively generating dispiro[4.2.5.2]pentadecanes 427... 

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