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Disintegrants deformation recovery

The deformation recovery theory implies that the shapes of the disintegrant particles are distorted during compression, and that the particles return to their preeompression shape upon wetting, thereby causing the tablet to break apart. Hess [20], with the aid of photomicrographs, showed that deformed stareh particles returned to their original shape when exposed to moisture. [Pg.277]

The deformation recovery theory implies that the shapes of the disintegrant particles are distorted during com-... [Pg.3557]

Because of the complexities involved, the mechanism of action of super disintegrants is not well understood. Some of the proposed mechanisms include water wick-ing, swelling, deformation recovery, particle repulsion, and heat of wetting. Water uptake is a necessary... [Pg.3566]

Figs. 25E and F show differences in the elastic recovery of substances after compression. Fig. 25E depicts the surface of an ASA-tablet containing 10% of sodium carboxylmethyl starch as a disintegrant. The plastically deforming ASA remains plain after... [Pg.3238]

See other pages where Disintegrants deformation recovery is mentioned: [Pg.273]    [Pg.283]    [Pg.290]    [Pg.242]    [Pg.3555]    [Pg.3561]    [Pg.277]    [Pg.3557]    [Pg.215]    [Pg.150]    [Pg.521]    [Pg.847]    [Pg.218]    [Pg.37]   
See also in sourсe #XX -- [ Pg.277 ]



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