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Disease-associated protein gene products

Cells of patients with Bloom syndrome (BS) have many chromosome breaks and a high frequency of sister chromatid exchanges, perhaps in an effort to correct these breaks. The body is small but well-proportioned.kk A somewhat similar disease, the Werner syndrome (WS), is associated with premature aging.11 The Bloom s protein BLM and the WS gene product WRN are both helicases related to E.coli RecQ. Protein BLM colocalizes with replication protein A as discrete foci in the meiotic synaptonemal complex.1 3 Protein WRN also seems to be associated with DNA replication. Defects... [Pg.1585]

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See also in sourсe #XX -- [ Pg.42 ]



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Associated Diseases

Disease genes

Disease production

Disease-associated gene products

Gene disease genes

Protein , association

Protein disease

Protein products

Proteins associated

Proteins disease associated

Proteins production

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