Directed Assembly of Homomeric Molecular Solids

This chapter is broadly divided into two subject areas. First, an overview of strategies for the directed assembly of homomeric 0-D, 1-D, 2-D and 3-D molecular architectures with specific, pre-determined, and desirable connectivities and metrics is offered. Second, a description of some design principles that have been devised and tested for the assembly of co-crystals, heteromeric molecular solids, is given. 

1 Hydrogen-bond Interactions - Essential Tools for Constructing Molecular 

Not only do these complementary supramolecular synthons bring molecules together, they also constrain the relative orientation of those components in much the same way as carbon-carbon double bonds impart specific stereochemistry to individual molecules. 

An increased degree of complementarity (triple [26], quadruple [27], or quintuple [28]) will increase selectivity but may also present considerable covalent synthetic challenges a balance has to be struck in order to develop cost-effective and versatile supramolecular synthesis. 

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Directed Assembly of Homomeric Molecular Solids 217 2.5.2.3.2 Halogen Halogen Interactions... 

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