Fludarabine Dipyridamole

DIPYRIDAMOLE ANTICANCER AND IMMUNOMODULATING DRUGS Possible 1 efficacy of fludarabine Uncertain Consider using an alternative antiplatelet drug... 

Because fludarabine phosphate is an analogue of adenine, the UK manufacturers warn that drugs that are adenosine uptake inhibitors, such as dipyridamole, may prevent the uptake of fludarabine into cells and reduce its efficacy. Dipyridamole should probably therefore be avoided in patients receiving fludarabine. 

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