Diprophylline

Chamical Nama 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-l H-purine-2,6-dione Common Nama (1,2-Dihydroxy-3-propyl)theophylline diprophylline... 

C3H7CIO2 96-24-2) see Chlorphenesin Diprophylline Doxofylline Guaifenesin Guanadrel lohexol lopydol Mephenesin... 

Note The dipping solution can also be used as spray solution. Since the chromatogram zones slowly fade in the air it is recommended that the chromatograms be covered with a glass plate for long-term storage. Color differentiation is possible with purine derivatives [6, 8]. Diprophylline is not colored [6]. 

Common Name (l,2-Dihydroxy-3-propyl)theophylline Diprophylline Structural Formula ... 

Antiasthma. Theophylline and diprophylline are eliminated slowly by the neonate observe the infant for irritability or disturbed sleep. 

A 39-year-old man presented with a gait disturbance confusion, hyperthermia (38.2 C), and hyperhidrosis after massive ingestion of a formulation containing diphenhydramine. With intensive support, including bromocriptine, he recovered within 12 days. The estimated dose of diphenhydramine was 40 mg x 60 tablets, and each tablet included 26 mg of diprophylline, a xanthine derivative. 

A 30-year-old woman developed a generalized urticarial reaction immediately after the intravenous administration of aminophylline (4). Skin intradermal testing was positive to ethylenediamine. Rechallenge was positive with intravenous aminophylline but negative with diprophylline, which does not contain ethylenediamine. 

The xanthines used in nnedicine are quite a homogenous group as regards UV spectra. All the compounds listed (caffeine [002], pentoxifylline [006], diprophylline [1406], etofylline [1407], theobromine [1414], theophylline [1415]) have a good, constant absorption band at 272 2 nm e approximately 9000-10000 in methanol minimum 242 2 nm (see figure 10). 

These chains are present in some classical drugs such as the muscle relaxant mephenesin and the bronchodilator dyphylline (diprophylline) " (Figure 38.22). More recent applications are found in the venotropic troxerutin and... 

Wenk, M. Eggs, B. Follath, F. Simultaneous determination of diprophylline, proxyphylline and theophylline in serum by reversed-phase high-performance liquid chromatography. J.Chromatogr., 1983, 276, 341-348... 

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