Diphosphoglycerate phosphatase

Rosa R, Gafilardon J, Rosa J. Diphosphoglycerate mutase and 2,3-diphosphoglycerate phosphatase activities of red cells comparative electrophoretic study. Biochem Biophys Res Commun 1973 51 536-42. 

Heat stability and other characteristics indicate that this enzyme may be identical with the acetyl phosphatase of Lippman (26), which also catalyzes the hydrolysis of 1,3-diphosphoglycerate (21). 

Figure 8.1 PolyP and PolyP-metabolizing enzymes during the growth of E. coli K-12 (1) biomass (2) PolyP (3) intracellular P (4) exogenous P, (5) exopolyphosphatase (6) tripolyphosphatase (7) alkaline phosphatase (8) polyphosphate kinase (9) l,3-diphosphoglycerate polyphosphate phosphotransferase (Nesmeyanova et al., 1973).

Figure 8.3 Effects of exogenous Pi on PolyP-metabolizing enzymes in E. coli (a) deficiency of exogenous P (b) excess of exogenous P (1) alkaline phosphatase (2) tripolyphosphatase (3) exopolyphosphatase (4) polyphosphate kinase (5) l,3-diphosphoglycerate polyphosphate phosphotransferase (Nesmeyanova et al., 1974b).

When the 1,3-diphosphoglyceric acid is formed, in reaction 5, DPN+ is reduced. The DPNH which results is first of all dehydrogenated by phosphodihydroxyacetone producing 3-phosphoglycerol, which is then hydrolysed by a phosphatase to form glycerol. This is the explanation of... 

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