1,2-diphenyl-1 -3,5-pyrazolidinedione

Chemical Name 4-butyl-1,2-diphenyl-3,5-pyrazolidinedione Common Name 3,5-dioxo-l, 2-diphenyl-4-n-butylpyrazolidine Structural Formula ... [Pg.1216]

Thiazolinobutazone. 4-Butyi-l, 2-diphenyl-3,5-pyrazolidinedione com yd will) 4,5-dili ydro-2-rh iuzolamine (f.-f) 2-thiazoline-2-ammonium 4-n-butyI-1,2-diphenyl 3,5-pyrazolidinedionate phenylbutazone 2-amino-2-thiazoline salt TZB LAS 11871 Fordonal. CmHwN4OjS mol wt 410.54. C 64-36%. H 6.38%, N 13.65%, O 7.80%, S 7.81%. A heterocyclic derivative of phenylbutazone. <. v. Prepn J. [Pg.1466]

Pentaacetylgitoxin-pengitoxin Peracon-isoaminile Phenopy razone-1,2-diphenyl-3,5-pyrazolidinedione Phyllocontin-aminophylline Primalan-mequitazine Proparacainc-proxymetacaine Protease 1-brinase... [Pg.393]

Venocuran, comb 1,2-diphenyl-3,5-pyrazolidinedione, plant extract, horse chestnut extract... [Pg.394]

Direct insertion mass spectrometry of the metabolite Rg, 0.26 (Table 3) gave a molecular ion of 352 indicating the insertion of two atoms of oxygen into the feprazone nucleus. Also notable was a prominent ion at m/e 200 implying oxidation of the diphenyl-pyrazolidinedione nucleus, the other oxygen presumably being in the side chain. Bakke ejt al. (4) had identified a dihydroxy metabolite of phenylbutazone in the rat, therefore a dihydroxy metabolite of a diphenylpyrazolidinedione was not without precedent. With these facts in mind -methoxy-3 -hydroxyfeprazone was synthesised and it and the metabolite methylated with diazomethane. The spectra of the methylated metabolite and the methylated reference compound were almost identical (Table 3). Thus the molecular ion in both spectra corresponds to the dimethylated -hydroxy-3 - hydroxyfeprazone. [Pg.10]

Chemical Name 4-(3-Oxobutyl)-1 -diphenyl-S.S-pyrazolidinedione Common Name Ketophenylbutazone... [Pg.858]

RN 27315-91-9 MF C25H32N4O2 MW 420.56 EINECS 248-398-7 CN 4-butyl-4-[(4-methyI-l-piperazinyl)methyl]-l,2-diphenyl-3,5-pyrazolidinedione... [Pg.1646]

C4H jCl202S 1633-84-7) see Sultiame 4-(3-chloro-2-butenyl)-l,2-diphenyl-3,5-pyrazolidinedione (C11JH17CIN2O2 10561-01-0) see Kebuzone l-chloro-3-(ert-butylamino-2-propanol... [Pg.2324]

Sidky, M.M., Soliman, F.M., and Shabana, R., Organophosphorus compounds. XIV. Reaction of dialkyl phosphites and thiol acids with 4-benzylidene-l,2-diphenyl-3,5-pyrazolidinedione, Egypt. J. Chem., 15, 79, 1972. [Pg.105]

Phenylbutazone Phenylbutazone, 4-butyl-l,2-diphenyl-3,5-pyrazolidinedione (3.2.6), is synthesized in a single stage by reacting hydrazobenzol with butylmalonic ester [68,69]. [Pg.40]

Sulfinpyrazone Sulfinpyrazone, l,2-diphenyl-4,2-(phenylsulfinil)ethyl-3,5-pyrazolidine-dione (3.2.8), is an analog of phenylbutazone that is synthesized in the analogous manner of condensing hydrazobenzol with 2-(2-phenyltioethyl)malonic ester into pyrazolidinedione (3.2.7), and the subsequent oxidation of thiol ether by hydrogen peroxide in acetic acid into the sulfoxide, sulfinpyrazone (3.2.8) [70,71]. [Pg.41]

Chemical Name l,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione... [Pg.3111]

Bonardi G, Vidi A (1973) Action of 4-phenyl-l,2-diphenyl-3,5-pyrazolidinedione (DA 2370) on an experimental hyper-uricosuria in the rat. Pharm Res Comm 5 125-129 Dan T, Yoneya T, Onoma M et al. (1994) Hypouricemic and uricosuric actions of AA-193 in a hyperuricemic rat model. Metabolism 43 123-128... [Pg.113]

C15H12N202 1,4-diphenyl-3,5-pyrazolidinedione 3426-01-5 25.00 1.2538 2 28313 C15HU03 methyl alpha-hydroxydiphenylacetate 76-89-1 25.00 1.1685 2... [Pg.272]

Synthetic methods involving conversion of other, but similar, ring systems to 3,5-pyrazolidinediones have been reduction of 1,2-diphenyl-3,4,5-pyrazolidinetrione with tin and hydrochloric acid63 and hydrolysis of 5-imino-3-pyrazolidinones (3-amino-2-pyrazolin-5-ones) with acid.1339,1596... [Pg.143]

Only two hydroxy- and alkoxy-3,5-pyrazolidinediones are known (Table XLVIII). 4-Butyl-4-hydroxy-l,2-diphenyl-3,5-pyrazolidinedione is formed as a by-product in the synthesis of 4-butyl-l,2-diphenyl-... [Pg.146]

Diphenyl-4[2-(phenylsulfinyl) ethyl]-3,5-pyrazolidinedione 3, 5-Pyrazolidinedione, 1,2-diphenyl-4-[2-(phenylsulfinyl) ethyl]- B.P.,... [Pg.293]

Synonyms 4-Butyl-l,2-diphenyl-3,5-pyrazolidinedione flexazone diphebuzol... [Pg.250]

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