2.4- Diphenyl-5-mcthyl

Diphenyl-j [1-(diphenyl-mcthyl-phos-phonio)-cydopropyl]-methyI - ... 

Athoxycarbonyl-athyliden)- 873 9-Alhoxycarlxmylmethylen- 873 9- 1-Alhoxycarbonyl-propylidcn)- 873 9-(Hydroxy-diphenyl-mcthyl(- 834 9-[9-Hydroxy-thioxatithenyl-(9)]- 834 9-( 1 -M elhoxycar bonyl-iithyl iden)- 873 9-(l-Methy1mercapto-2-oxo-propylidcn)- 873 9-Oxo-2,3.8-trihydroxy- 670... 

A suspension of 11 g (50 mmol) of freshly sublimed cyclopentadienyltitanium trichloride in 400 mL of Ft.O (distilled over Va/benzophcnone) is treated with 23.2 g (50 mmol) of (/ ,/ )-4.5-bis[hydroxy(diphenyl)mcthyl]-2.2-dimethyl-1.3-dioxoIane under argon. After 2 min at r.t., a solution of 12.65 g (110 mmol) of Et5N in 125 mL of Et,0 is added dropwise to the very efficiently stirred mixture over 1 h. Stirring is continued for 12 h. The precipitated Ei, N HC1 (13.8 g) is filtered off under argon and washed three times with 50-mL portions of Ft20. This stock solution (610 mL) is assumed to be 82 mM and can be directly used for further applications. The complex can be isolated by concentration of the stock solution to ca. 75 mL and addition of 300 mL of hexane. After stirring for 30 min. the suspension is fdtered and the residue washed three times with 10-ml. portions of hexane yield 26.8 g (87%) of the pure product. 

N-Trichlor- 699 Trichlor-N,N-diathyl- 570 Trichlor-N,N-diphenyl- 570 Trifluor-N,N-dimethyl- 239 Trifluor-N-mcthyl- 239... 

Methyl-1-athyliden- 402 2-Mcthyl-l,l-diphenyl- 391 2-Mcthyl-l-heptyl- 676 Methyl-hydroxymethyl-... 

Mcthyl-2-phenyl- 436 2-Oxo-3,4-diphenyl- 136f. 2-Oxo-5-(2-methoxy-phenoxymethyl)- 132... 

Oxo-2-thiono-5-(3-carboxy-propyl)-1-phenyl- 252 4-Oxo-2-thiono-l,5-dimethyl- 252 4-Oxo-2-thiono-5,5-diphenyl- 252 4-Oxo-2-thiono-l-mcthyl-5-phenyl- 252 4-Oxo-2-thiono-5 -methyl-1 -phenyl- 252 4-Oxo-2-thiono-4-(2-methyl-propyl)- 252 4-Oxo-2-thiono-l-phenyl- 252 2-Thiono-5,5-diphenyl- 252... 

Treatment of tt-methylstyrene oxide with f ri-butylmagnemuii chloride or phenylmagneaium bromide has been reported 24 171 p. yield 4,4-dimethyl 2phemyl-S-pentanol and 1.2-diphenyl-1-propanol respectively (Eq. 843). Both products presumably arise from methyl-phenylsoetsldehyde, formed by preliminary isomerization of a-mcthyl-styrene oxide. 

Diphenyl-2-fluoro-1 -mcthyl-ElOa. 111 [(1-OH —alkylpcyclo-propan + HF]... 

This procedure offers an extremely simple and fairly general method for the preparation of 2,6-disubstituted 4-pyrones. Pyrones which have been prepared2 by this procedure are 2-methyl-6-phenyl-4-pyrone (60%), 2-(J>-chlorophenyl)-6-mcthyl-4-pyrone (90%), 2,6-diphenyl-4-pyrone (91%), 2-( -chloro-phenyl)-6-phenyl-4-pyrone (90%), 2-phenyl-6-(3-pyridyl)-4-py-... 

CN 5,5-diphenyl-3-l(phosphonooxy)mcthyl]-2,4-imidazolidincdione disodium salt... 

CN butanedioic acid mono[(4-butyl-3,5-dioxo-l,2-diphenyl-4-pyra/.olidinyl)mcthyl] ester... 

Diazo-ethoxycarbonyl-mcthyl)-diphenyl- E2, 220 f l-Diazo-2-(2-furyl)-2-oxo-ethy[]-diphenyl- El, 592 (Diazo-methyl)-diphenyl- El, 586f, E2, 145, 220 (l-Diazo-2-oxo-2-phenyl-ethyl)-diphenyl- El, 593... 

Methylpiperazin-l-ylmagnesium bromide (made in situ) and crude 3-chloro-4-methylthio-l,l-diphenylsilolane (228) [made in situ from the 2,5-dihydrosilole (227), Me2S2, and S02C12] gave l-mcthyl-4-(4-mcthylthio-l,l-diphenyl-silolan-3-yl)piperazine (229) (THF, 20°C, 12 h 50%, as oxalate salt).1182... 

It is interesting to note that 5-nitrobenzoxazole has two absorption maxima 224 (4.39) and 270 nm (3.84), while 6-nitrobenzoxazole shows only one maximum in area Amix 282 nm (4.01) [1200], A similar pattern is observed for 5-nitro- and 6-nitro-2-alkyl(aryl)benzoxazole too. The available experimental data are not enough to explain spectral differences of this kind. Apparently, it would be well to carry out quantum-chemical calculations or to involve other physical-chemical methods. An investigation of chromophoric 2-(4 -diphenyl)-5-nitrobenzoxazole with the help of UV (A 305 nm), fluorescence and laser spectroscopy has been reported by Chinese chemists [1201], Chromophores 2-(2 -hydroxy-4 -aminophenyl)-6-nitrobenzoxazole [ 1202], 2- [4-[4-(V,V-dihydroxyethyl-amino)-phenylazol]-phenyl -6-nitrobenzoxazole, 2-[4-(/V-mcthyl,V-hydroxyethyl-amino)... 

Thiabenzene I-oxide. The reaction of 1,3-disubstituted 2-propynones such as l,3-diphenyl-2-propyn-I-onc (1) with dimethyloxosulfonium methylide in DMSO at 16.5° gives l-mcthyl-3,5-disubstituted thiabenzene I-oxides in the case of (I) the product is l-methyl-3,5-diphenylthiabenzene l-oxide (3), obtained in 76% yield. If the reaction is carried out in THF-DMSO at - 8°, the intermediate (2) can be isolilted it probably arises by Michael addition of the reagent to (I). 

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