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Dioxygenases increased specificity

Tryptophan dioxygenase (Section 8.3.2) is only found in the liver other tissues have an indoleamine dioxygenase, with lower specificity, that catalyzes the same reaction. However, the pathway for onward metabolism of kynure-nine is found only in liver and mononuclear phagocytes, and induction of indoleamine dioxygenase by cytokines, such as interferon-y, leads to increased circulating concentrations and urinary excretion of kynurenine, with litde or... [Pg.208]

Aniline dioxygenase Acinetobacter sp. strain YAA Saturation mutagenesis and error-prone PCR V205A/I248L/S404C Increased activity Widened substrate specificity to include 2,4-dimethylaniline and 2-isopropylaniline [20]... [Pg.460]

See other pages where Dioxygenases increased specificity is mentioned: [Pg.467]    [Pg.92]    [Pg.460]    [Pg.652]    [Pg.121]    [Pg.242]    [Pg.441]    [Pg.223]    [Pg.229]    [Pg.232]    [Pg.341]    [Pg.306]    [Pg.306]    [Pg.30]    [Pg.85]    [Pg.260]    [Pg.1116]    [Pg.335]    [Pg.1585]    [Pg.2870]    [Pg.4512]    [Pg.158]    [Pg.183]    [Pg.462]    [Pg.48]   
See also in sourсe #XX -- [ Pg.460 ]



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Dioxygenases

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