3-Dioxol-2-one

Condensation of benzyl glycinate -toluenesulfonate salt with 4,5-diphenyl-1,3-dioxol-2-one affords 154, which can be converted to the 4,5-diphenyl-3-substituted-2(3//)-oxazolones 155 by sequential treatment with an aldehyde/LiHMDS followed by diaminosulfur trifluoride (DAST). Hydrogenolysis then affords the p-fluoro-a-amino acids 156 in excellent yields without any concomitant cleavage of the... 

To a mixture of the iodonium salt (172 mg, 0.46 mmol) and palladium acetate (4 mg, 5 mol%) was added sodium bicarbonate (77 mg, 0.92 mmol) followed by the cyclic carbonate (110 mg, 0.46 mmol) in DMF (5 ml), under nitrogen, at room temperature. After stirring for 2 h, the reaction mixture was quenched with saturated aqueous ammonium chloride solution and extracted with ether (2 x 20 ml). The extract was dried, the solvent removed and the residue chromatographed on silica (ethyl acetate-hexanes 1 4) to afford 4-phenylvinyl-5-benzyloxymethyl-1,3-dioxol-2-one (140 mg, 97%), m.p. not given. 

The carbonylation of the sodium salt of an enediolate, prepared in situ from PhC(0)C(0)Ph, with COClj gives the 1,3-dioxol-2-one derivative [270] ... 

The dienophilic properties of vinylene carbonate (1,3-dioxol-2-one, 6) have been repeatedly exploited for the synthesis of cyclic polyols. Recently a number of ribofuranose derivatives have been synthesized starting from 6. The known adduct 7, obtained from 6 and furan, was c/r-hydroxylated, and after acetonation was hydrolyzed with base and cleaved with permanganate to give the dicarboxylic acid 8. The corresponding anhydride 9 gave, on treatment with trimethylsilyl azide, the isocyanate 10, which in turn was converted into the carbonate 11 on addition of methanol. The monoester 12, obtained in the reaction of anhydride 9 with isopropanol, was effectively resolved into enantiomers by the use of brucine or (/ )-l-(2-naphthyl)ethylamine. ... 

Dioxane 1,4-Dioxane-2,5-dione 1,4-Dioxane-2,6-dione Dioxathion 1,3-Dioxepane 1,3-Dioxolane 1,3-Dioxol-2-one Dioxybenzone... 

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