Diolefinic linkers

Diolefinic linkers Cleavage Product after cleavage ... 

Figure 8.6 Hydrophilic NBE monomers (11 and 13) and diolefinic cross-linkers (12 and 14) used to make hydrogels.

The same linker type has also been used by other groups for example Waldmaim et al. [368,369] and Blechert et al. [370] to release terminal alkenes. The synthesis of the linker affords the addition of diolefinic structures 725 that have to be prepared via a three-step synthetic route to Mer-rifield resin 1. After removal of the alcoholic protection group on the bead, substrates 727 like, for example, saccharides can be anchored on the resin, modified via diverse steps and cleaved to give compounds 730 (Scheme 108). 

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