Dinuclear site Dioxygen

Interaction of dioxygen species with Fe aq and with Fe " aq has been very briefly reviewed. In relation to 0x0-, peroxo-, and superoxo-complexes as models for intermediates in oxygenase activity, a brief report on a 2000 symposium on activation of oxygen summarizes the then-current situation in the search for a mechanism common to mono- and dinuclear iron sites, mono- and dinuclear copper sites, and copper-iron sites. The outline proposals comprise ... 

Cobalt Inorganic Coordination Chentistry Copper Hemocyanin/Tyrosinase Models Copper Inorganic Coordination Chemistry Copper Proteins Oxidases Copper Proteins with Dinuclear Active Sites Iron Heme Proteins Dioxygen Transport Storage Iron Heme Proteins, Mono- Dioxygenases Iron Models of Proteins with Dinuclear... 

Nature sometimes solves identical problems with apparently quite different solutions. Important examples of such a convergent evolution at the molecular level are the functional parallels between iron and copper centers in bioinorganic chemistry. The dioxygen-carrier proteins of different organisms may, for instance, be based on mononuclear iron tetrap5rrrole complexes or in contrast may involve dinuclear copper sites 10). S5mthetic chemistry can even go a step fiuther and try to mimic basic... 

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