3.4- dimethyl-6-propyl-4,5-dihydro

Guanidin 4-Cyan-l,3-dibutyl- E4, 1303 (SR - NR2) lH-Tetrazol 4-(2,2-Dimethyl-propyl)-5-isopropyliden-1 -methyl-4,5-dihydro- E15/2, 2065 [Tetrazolium ( —HX)]... 

Dioxo-3-ethyl-l, 5,6,7-tetrahydro- 677 Pyrazolo[3,4-d]-l, 3-oxazin l,3-Dimethyl-4-oxo-6-(2-oxo-propyl)-dihydro- 557 1- Acyl-3-methylthio-6-oxo-l,6-dihydro- 676 2- Benzyl-6-(4-nitro-phenyl)-4-oxo-2,4-dihydro-676 4-Amino-7-chlor-phenyl- 976 2-(4-Aminosulfonyl-phenyl)-4,7-dichIor- 977 2-(4-Aminosulfonyl-phcnyl)-4,7-dihydroxy- 922 4-Anilino-7-chlor-2-(3-thienyl)- aus 4,7-DichIor-2-(3-thicnyI)- pyriclazino-[4,5-d]-l,3-thia7.ol)/Ethanol 976 7-Chlor-4-ethoxy-2-methyl- 972 7-Chlor-4-methoxy-2-phenyl- 972 7-ChIor-4-(3-pyrroIidino-propyloxy)-2-(2-thienyI)- 972... 

Chamical Nama 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-l H-purine-2,6-dione Common Nama (1,2-Dihydroxy-3-propyl)theophylline diprophylline... 

Chemical Name 3-Pyridine carboxylic acid compounded with 3,7-dihydro-7-[2-hydroxy-3-[(2-hydroxymethyl)methylamino] propyl] -1,3-dimethyl-1 H-purlne-2,6-dlone(1 1)... 

CN 7-t3-[[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]amino]propyl]-3,7-dihydro-1,3-dimethyl- lW-purine-2,6-dione... 

Bromophenylazo)-2-propyl hydroperoxide, 3156 l,2-Dihydroperoxy-l,2-bis(benzeneazo)cyclohexane, 3762 (Y-Phcnylazobcnzyl hydroperoxide, 3609 a-Phenylazo-4-bromobenzyl hydroperoxide, 3607 1-Phenylazocyclohexyl hydroperoxide, 3539 a-Phenylazo-4-fluorobenzyl hydroperoxide, 3608 3,3,5-Triphenyl-4,4-dimethyl-5-hydroperoxy-4,5-dihydro(3H)pyrazole, 3841... 

To 10.5 mmol of lithium diisopropylamide in 23 mL of THF at — 78 C under nitrogen are added 3.21 g (10 mmol) of (45,55)-4,5-dihydro-4-melhoxymethyl-5-phenyl-2- 3-(trimethylsilyloxy)propyl]oxazole in lOmL of THF. After the mixture is stirred for 0.5 h, the yellow solution is cooled to —98 C and 1.0 mL (10.5 mmol) of dimethyl sulfale is added neal, dropwise. Stirring is continued for 2 h at 98 G, and then the solution is slowly warmed to r.t. 

Als Base dient hierbei ein doppelter OberschuB an Amin. Die Produkte (z.B. Bis-[l,l-diethyl-propinyl]-amitv, 48%) konnen, je nach Bedingungen, zu sterisch stark gehinderten primaren Aminen (z. B. H2/Pt02/Ethanol, 300 kPa 3-Amino-3-ethy -pentan 90%), sekundaren Aminen (z.B. H2/Raney-Ni/Ethanol, 420kPa Bis-[1, l-diethyl-propyl]-amin 72%) Oder cyclischen Aminen (z.B. Hj/Pd-C/Ethanol, Normaldruck, 0° 2,2,5,5-Tetra-ethyl-3,4-dimethyl-2,5-dihydro-pyrrol, 48% neben 2,2,5,5-Tetraethy -4-methyl-3-methylen-pyrrolidin 15%) hydriert werden. 

Upon prolonged storage of the reaction mixtures at room temperature, 6-acetyl-2,5-dimethyl-2-(2,3-dioxo-l-propyl)-3,4-dihydro-[2H]pyrane (5) is formed. As was shown in separate experiments, 5 is a dimerisation product of the unsaturated diketone 2 and can be converted back to 2 in quantitative yield by passing it through a hot glass tube at 400°C. In table 1 the isomerization of 1 — 4 was not considered to be conversion, since it was shown in a separate experiment that 4 is converted into 2 in a similar rate to that of i — 2. 

Yelinova et al. reported the oxidation of iV-[2-hydroximino-2-methyl-l-(2-pyridyl)propyl-2]hydroxylamine 239 using sodium hypobromide, generated from bromine and sodium hydroxide in cold condition (0°C), to furnish 3-bromo-3,4-dihydro-4,4-dimethyl-3-(2-pyridyl)-l,2-diazet-l,2-dioxide 240 in 26% yield (Equation 30) <2003MI395>. These oxides were evaluated for their NO donor activities in biological systems. During the last decade, not many new syntheses of diazetidines have been reported. 

CN 3,7-dihydro-1-(2-hydroxy propyl)-3,7-dimethyl-1 f/-purine-2,6-dionc... 

Another remarkable example of a solvent-induced ehange in enantioselectivity is the partial hydrolysis of achiral 4-aryl-substituted l,4-dihydro-2,6-dimethyl-3,5-pyridine diearboxylie diesters, catalysed by a lipase from Pseudomonas sp., leading either to the (P)- or (5)-eonfigured monoesters. Whereas in water-saturated di-/-propyl ether, the S)-monoesters are obtained with ee values up to 99%, the (P)-monoesters are formed in water-saturated eyclohexane with ee values of 88-9 l%i [316]. 

Dimethyl-2-ethyl-6-propyl-3,4-dihydro- E14a/2. 744 (En-N-En 4- CH20) Oxaziridin 3-Butyl-2-cyclohexyl-X/4, 460... 

DIHYDRO-5-(3-(DIMETHYL-AMINO)PROPYL)-5H-DIBENZ-(b,f)AZEPINE HYDROCHLORIDE... 

SYNS ANTIDEPRIN HYDROCHLORIDE BERKOMINE CENSTIM CENSTIN CHIMO-REPTIN CHRYTEMIN CO CAP IMIPR. tMINE 25 DEPRINOL 10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ(b,f)AZEPINE-5-PROPANAMINE MONOHYDROCHLORIDE 5-(3-DIMETHYLAMINO-PROPYL)-... 

Complexation of dihydronaphthalene with chromium tricarbonyl facilitates the attack of a nucleophilic amine and stereoselectively directs the protonation "anti" to the metal atom. (+)-(l S,2 R)-, 2-Dihydro-7-methoxy-1,4-dimethyl-1 - 2 -[methyl(trifiuoroacetyl)amino]propyl -naphthalene [(+)-7] was treated with chromium hexacarbonyl to give a mixture of a- and /(-chromium tricarbonyl complexes in a 10 1 ratio ( H NMR). The complexes were separated and the a-isomer cyclized by base treatment and sonication. Dccomplexation gave the ben-zomorphan tricycle 8 in low yield [40%, based on recovered (+)-7]18. The trifluoroacetyl protection of the amino group was necessary to achieve both stereoselective complexation with chromium tricarbonyl and successful cyclization. 

The reaction of 2-isopropyl-5,5-dimethyl-5,6-dihydro-2//-l,3-oxazine 306 with MCPBA leads to formation of the corresponding A -alkyl oxaziridine 307 as a single isomer <1995T139>. Due to the preferential conformation of imine 306, the imine double bond is exclusively oxidized anti to the f-propyl moiety. Oxidation of imine 308 with MCPBA gave oxaziridine nitroxide 309 in 90% yield <2000TL8787> and similar oxidation of 310 gave oxaziridine 311 in 74% yield <2005S1496>. 

C11H12N20 1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazor 60-80-0 592.15 52.805 1,2 21957 C11H13N 2-propyl-1 H-indole 13228-41-6 533.83 47.144 2... 

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