5-Dimcthylamino-2-phenyl

Diethyl-(4-methoxy-methyl-anilino)- E2, 296 Diethyl-(N-methyl-anilino)- E2, 295, 296 Diethyl-phenoxy- El, 2SI Diethyl-phenyl- -phenylimid XU/1, 177 Difluor-difluormethyl- E2, 836, 854 Difluor-(fluorsulfonyl-methyl)- E2, 857 Difluor-methyl- E2, 836, 854 Difluor-phenyl- E2, 854 Difhior-trifluormethyl- E2, 905 Difluor-triphenyl- E2, 881 Diisopropyloxy-hexyl- El, 135 Diisopropyloxy-methyl- E2, 200, 480 Diisopropyloxy-phenyl- E2. 134, 135, 207 Diisopropyloxy-propyl- E2, 200 Dimcthoxy-methyl- E2, 480 Dimethoxy-phenyl- E2, 204ff, 207, 393, 856, 864 Dimethylamino-diphenyl- E2, 18, 227 Dimethylamino-ethinyl- E2, 230 Dimethylamino-fluor-trifluormethyl- E2, 435 (4-Dimethylamino-phenyl)-diphcnyl- E2, 108 (4-Dimcthylamino-phenyl)-diphcnyl- -(2-nitro-phenylthioimid) E2, 108 Dimethylamino-l-propinyl- E2, 230 (l,l-Dimethyl-butyloxy)-ethyl-methyl- E2, 20, Dimethyl-(diphenylmethylen-amino)- E2, 106 Dimethyl-fluor- E2, 161 Dimethyl-phenyl- E2, 99, 103 Dimethyl-phenyl- -(2-aminocarbonyl-hydrazinocar-bonylimid) E2, 113... 

Dimethylaminophenyl4-Flnorophenyl Tellurium Dichloride In a 250 ml flask fitted with a reflux condenser are placed 16.5 g (50 mmol) of 4-fluorophenyl tellurium trichloride, 19.0 g (50 mmol) of 4-dimcthylamino-phenyl mercury acetate, and 100 ml of absolute dioxane. The mixture is heated under reflux for 8 h during which time it acquires a dark violet color. The mixture is allowed to cool to 20", the precipitated mercury(II) chloride/dioxane adduct is filtered off, and activated charcoal is added to the filtrate which is then heated under reflux for 30 min. The mixture is allowed to cool and is then passed through a layer of aluminum oxide. The filtrate is concentrated to one-fourth of its original volume by distillation, the concentrate is diluted with 100 ml of hexane to precipitate the product which is filtered off, washed with hexane, dried, and recrystallized from propanol yield 7.2 g (35%) m.p. 145°. 

A 30% ee is obtained by reducing 2-chloroacetophenone with racemic l-(4-dimcthylamino-phenyl)ethanol in the presence of the optically active ligand 26c and 0.2 equiv of 7,r(0-r-Bu)4u and 62% in the presence of ligand 26d209 (see ref 210). 

A similar reaction of 5-oxo-4-phenyl-4,5-dihydro-l//-l,2.4-bcnzotriazepine-3-carbonyl chloride with 2-(dimethylamino)ethanol gave 2-(dimcthylamino)elhyl 5-oxo-4-phenyl-4,5-dihydro-l U-, 2,4-benzotri-azcpine-3-carboxylate (11c) yield 54% mp 130-132 C. 

Methoxy-l-phenvl- 493 2-Methyl- 101, 414. 512 2-Methylamino-3-dimcthylamino-l-phenyl-... 

Methane Difluoro-dimcthylamino-(4-nltro-phenyl)- ElOa, 376 (CO -> CF2) ... 

CnH oN2 883-40-9) see Benzatropine Cefbuperazone Cefixime Cefoxitin t i.v-Cefprozil Cibenzoline Latamoxef (/LS, /f,S)-I,2-diphenyl-l- 4- 2-(dimethylamino)ethoxy] phenyl Jbutane-1,4-diol (CmH., NO, 141854-25-3) see Toremifenc (Z)-l,2-diphenyl-l-[4-(2-(dimcthylamino)ethoxy)phenyl -... 

Dimcthylamino-tributylphosphoniono- El, 576 (4-Methoxy-phenyl)-tributylphosphoniono- El, 576 Natrium-dibutyl- E2, 263 Natrium-diethyl- -Bis-hydrat... 

Hester, J. B., New synthesis of 8-chIor-I-[2-(dimcthylamino)cthyl)-6-phenyl-4H-s-tria-zolo 4,3-a) l,4]-benzodiazepinc, which has antidepressant properties, J. Org. Chem.. 44, 4165, 1979. 

DiethylaminO 3-oxo-2.4,5-triphenyl-2,3-dihydro- 3043 2-Dimethylamino-4,5-diphcnyl-1-methyl-2-(4-melhyl-phenyl)-3-oxo-i,3-dihydro- 3043 2-Dimcthylamino-1-ethyl-3-oxo-2,4,5-triphenyl-2,3-dihydro- 3043... 

Dimcthylamino-4-phenyl- 14, 158 2-(4-Dimethylamino-phenyl)-4-methyl-5-(4-nitro-phenyl)-170... 

Benzyl-3(5)-hydroxy-5(3)-phenyl- 644 4- Benzylidenamino- 564 4-Benzylidenamino-3,5-bis-[methylthio]- 565 4-Benzylidenamino-3(5)-dimcthylamino-5(3)-methoxy- 565... 

A thyl-( 2-methyl-propyl)-piperidyl-( 3)- 2 60 (2-Amino-athyl)-butyl-(2)-cyclopentyl- 132 (2-Amino-athyl)-(2-dimethylamino-athyl)- 132 (2-Amino-athyl)-(3-dimcthylamino-propyl)- 132 (2-Amino-athyl)-(2-piperidino-athyl)- 132 (2-Amino-athyl)-(3-piperidino-propyl)- 132 (2-Amino-athyl)-propyl-butyl-(2)- 132 (2-Amino-athyl)-propyl-pentyl-(2 bzw. 3)- 132 (2-Amino-ben7yl)-benzyliden- 230 (4-Amino-phenyl)-(4-ch or-benzyliden)- 224 Aryl- 742ff. 

The combined acidic phases are made alkaline (pH > 11) with 10% aq sodium hydroxide and extracted with ethyl acetate. The organic layers are combined, washed with sat. aq sodium chloride, and dried, Filtration and concentration in vacuo gives a mixture of ( —)-2-dimethylamino-l-phenyl-l-propanol and A-ethylben/enamine as a mixture of crystals and oil (2.41 g, - 100%). This is subjected to bulb-to-bulb distillation, giving A-cthylbenzenamine as an oil (1.32 g, 98%), and (-)-2-dimcthylamino-Tphenyl-l-propanol (0.82 g, 82%) without raccmization mp 87.5-89.5°C [a] 0 —29.0 (c = 6.50, CH,OH) 98% ee. 

---