1.3- Dihydroxypropanone

It seems unlikely that this reaction could occur in quite the same way as in the laboratoryaldol reaction, because the enolate anion of the donor molecule (dihydroxypropanone) is not expected to be formed in significant amount of the pH of living cell. In fact there is strong evidence that the enzyme behaves as amino (ENH2) compound and reacts with carbonyl group of dihydroxy propanone to form an imine. This implies that the imine form of dihydroxy propanone is a key intermediate in the overall aldol-type addition. 

This implies that the imine form of dihydroxypropanone is a key intermediate in the overall aldol-type addition. 

Figure 7.2.1. Cellulose pyrolysate obtained at 59CP C and trimethylsilylated. The separation was done on a methyl silicone with 5% phenyl silicone type column. 1 1,2-dihydroxyethane, 2 2-hydroxypropionic (lactic) acid, 3 hydroxy acetic (glycolic) acid, 4 turanmethanol, 5 peak from silylation reagents, 6 1,3-dihydroxypropanone, 7 1,4-dioxane-2,5-diol, 8 1,3-dioxolane-4,5-diol, 9 1,3-dihydroxybenzene, 10 2-methyl-1,4-dioxane-2,5-diol, 11 1,4-dihydroxybenzene, 12 3-hydroxy-2-(hydroxymethyl)-2-cyclopenten-1-one, 13 2-hydroxy-5-(hydroxymethyl)-4(H)-pyran-4-one, 14 1,2,3-trihydroxybenzene, 15 internal standard, 16 an anhydrosugar, 17 levoglucosan (1,6-anhydro-p-D-glucopyranose), 18 a monosaccharide, 19 an anhydrosugar, 20 an anhydrosugar, 21 1.6-anhydro-P-D-glucofuranose .

Beilstein Handbook Reference) AI3-24477 BRN 1740268 CCRIS 4899 Chromelin Dihydroxyacetone 1,3-Dlhydroxyacetone 1,3-Di-hydroxydimethyl ketone 1,3-Dihydroxypropanone Dihydroxyacetone Dihyxal EINECS 202-494-5 Ketochromin NSC-24343 Otan Oxantin Oxatone 2-Propanone,... 

Y. Araki, J. Nagasawa, and Y. Ishido, "Synthesis of DL-apiose derivatives by photochemical cycloaddition of 1,3-dihydroxypropanone-2, J. Chem. Soc., Perkin /, 12 (1981). 

Glyceraldehyde is a common name the lUPAC name for this monosaccharide is 2,3-dihydroxypropanal. Similarly, dihydroxyacetone is a common name its lUPAC name is 1,3-dihydroxypropanone. The common names for these and other monosaccharides, however, are so firmly rooted in the literature of organic chemistry and biochemistry that they are used almost exclusively to refer to these compounds. Therefore, throughout our discussions of the chemistry and biochemistry of carbohydrates, we use the names most common in the literature of chemistry and biochemistry. 

Dihydroxypropanone, more commonly known as dihydroxyacetone, is the active ingredient in artificial tanning agents such as Man-Tan and Magic Tan. 

In the next step, FDP is broken into two three-carbon units, dihydroxyacetone phosphate (1,3-dihydroxypropanone phosphate, CH20HC0CH20P03, 5) and glyceraldehyde-3-phosphate (6), which exist in mutual equilibrium. Only the glyceraldehyde-3-phosphate is oxidized by NAD to pyruvate ion, with formation of two ATP molecules. As glycolysis proceeds, all the dihydroxyacetone phosphate is converted to glyceraldehyde-3-phosphate, so the result is the consumption of two NAD molecules and the formation of four ATP molecules per molecule of glucose. 

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