Digoxin pediatric elixir

Elixirs are sweetened hydroalcoholic oral solutions that are specially formulated for oral use in infants and children. Digoxin, a non-ionizable cardiotonic glycoside, is practically insoluble in water and is solubilized in propylene glycol, 10% ethanol, flavor, sweetener, preservative, and buffers to 50pg/ml in Lanoxin Elixir Pediatric from which the oral bioavailability of digoxin is 70-85%. Phenobarbital, an anticonvulsant and sedative with an intrinsic water solubility of 1 mg/ml, is solubilized in water, 23% ethanol, glucose, sodium saccharin, and flavors to 3.5 mg/ml in Donnatal Elixir. 

Binary 40% Propylene glycol and 10% Ethanol PEG/propylene glycol Lanoxin Elixir Pediatric (Digoxin) Ghildren s Tylenol Cold (Acetaminophen, chlorpheniramine maleate, and dextromethorphan)... 

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