Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Digitoxigenin glycoside

Digitoxigenin glycoside) (cardenolide, cardiac glycoside) D. viridifbra (Scrophulariaceae) [leaf] toxic]... [Pg.132]

Qualitatively, the cardiotonic activity of the glycosides resides in the aglycon portion,2 which is steroidal in nature. The most widely studied aglycons are digitoxigenin [3/3,14/9-dihydroxy-5/9-card-20(22) -enolide (1) ],... [Pg.273]

Scheme 5. Digitoxigenin and uzarigenin as aglycons of cardiac glycosides... Scheme 5. Digitoxigenin and uzarigenin as aglycons of cardiac glycosides...
The data obtained here without the special treatment of the glycosidic bonds differ from the expectation of the conformation based on activity studies. P-D-Digitoxosyl-o-digitoxigenin is calculated to have an energy of approximately 7 kcal/mol above the energy minimum for the proposed binding conformation. [Pg.202]

One of the first attempts to synthesize cardiac glycosides was made by Zorbach et al. in 1963 [102] by Fischer glycosylation. After treatment of digitoxigenin and unprotected digitoxose in dioxane with a saturated solution of hydrogen chloride in dichloromethane, 5.4% of the a- and 4.5% of the desired (5-glycoside were isolated after chromatographic purification. [Pg.317]

Glycosides of the gitoxigenin series are less active than the corresponding members of the digitoxigenin-derived series. Digitoxin is the only compound routinely used as a drug, and it is employed in congestive heart failure and treatment of cardiac arrhythmias, particularly atrial fibrillation. [Pg.246]

Cardiac glycosides (digoxi- NPS ODS-2, 1.5 pm genin, digoxin, digitoxigenin)... [Pg.417]

Cardiac glycosides (digitoxigenine, digitoxigenine-bis-digitoxoside, digitoxigenine-mono-digitoxine) Clenbuterol, salbutamol, methadone Neostigmine, salbutamol, fenoterol Salbutamol, salmeterol... [Pg.355]

Digitoxin (= Digitoxigenin 3- O-tridigitoxoside) (cardenolide, steroid triterpene glycoside)... [Pg.407]

See other pages where Digitoxigenin glycoside is mentioned: [Pg.335]    [Pg.318]    [Pg.320]    [Pg.508]    [Pg.335]    [Pg.318]    [Pg.320]    [Pg.508]    [Pg.138]    [Pg.423]    [Pg.23]    [Pg.12]    [Pg.17]    [Pg.989]    [Pg.114]    [Pg.210]    [Pg.114]    [Pg.239]    [Pg.198]    [Pg.59]    [Pg.70]    [Pg.198]    [Pg.289]    [Pg.289]    [Pg.290]    [Pg.301]    [Pg.302]    [Pg.312]    [Pg.313]    [Pg.315]    [Pg.1548]    [Pg.243]    [Pg.246]    [Pg.249]    [Pg.358]    [Pg.64]    [Pg.1114]    [Pg.3]    [Pg.354]    [Pg.42]    [Pg.71]   
See also in sourсe #XX -- [ Pg.508 ]



SEARCH



Digitoxigenins

© 2024 chempedia.info