Difficulty in thinking

All the hypnotic subjects reported boredom and apathy. Their voices became flat and their expressions listless. One subject became hostile and mildly sadistic. All hypnotic subjects reported difficulty in thinking, and two seemed to become paranoid in the trend of their thinking. One subject reported transient visual and auditory hallucinations, which he did not specify, and transient enhancement of visual and taste sensations. This same subject reported, "... distant objects seemed more distant and unreal than usual, while objects close to me were vivid and dazzling."... 

Scopolamine and other antimuscarinic drugs produce delirium with fluctuating levels of awareness, disorientation, marked difficulty in thinking, marked loss of memory, and bizarre delusions. Most subjects, at least under experimental conditions, find these drugs to be unpleasant and have little desire to repeat the experience. 

Tolerance to the effects of phencyclidine develops in both animals and man. A slight physical dependence has been reported in man, characterized by a craving for the drug, persistent amnesia, slurred speech and difficulty in thinking, which may last up to 1 year after discontinuing the drug. Severe personality changes have also been reported. 

Marijuana is a mixture of dried flowers and leaves from the plant Cannabis sativa. It is known by other names such as weed, pot, herb, Mary Jane, boom, gangster, and chronic. People use marijuana in the form of cigarette or in pipes. It also is often mixed with foods or brewed tea. Marijuana use affects the CNS as observed with memory and learning, difficulty in thinking, loss of coordination, increased heart rate, and anxiety. 

Mild acute and chronic intoxication from barbiturates is similar to that associated with alcohol, including symptoms of sluggishness, slurred speech, poor memory, and difficulty in thinking. Its effect with alcohol, another CNS depressant, is additive. Death can occur from intake of barbiturates with large amounts of alcohol. 

Some patients complain of sleepiness/ tiredness, difficulty in thinking, and dizziness after sumatriptan [10 ], and in a meta-analysis, sumatriptan 100 mg caused 6% more nervous system adverse events than placebo, and zolmitriptan 2.5 mg caused 9% more [ll ]. 

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