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Differential scanning calorimetry in the study of lipid structures

3 Differential scanning calorimetry in the study of lipid structures [Pg.6]


CH4 DIFFERENTIAL SCANNING CALORIMETRY IN THE STUDY OF LIPID STRUCTURES... [Pg.48]

Differential scanning calorimetry is a well known technique in the study of the thermal behavior of lipids and can be used to assess purity and stability of lipids, perturbation of aggregate structures, phase transition temperatures, lipid mixing behavior, and influence of other molecules and ions on structure. ... [Pg.981]

There is independent physical evidence for non-uniform distribution and restriction from transmembrane diffusion of a-Toc in lipid membranes. Differential scanning calorimetry results indicated that it partitioned into the most fluid domains in lipid vesicles. Fluorescence studies showed that a-Toc has a very high lateral diffusion rate in egg lecithin but it does not take part in transbilayer (flip-flop) migration even over many hours . It is not known if this behavior of a-Toc extends to natural biomembranes where actual structures and conditions may dramatically change migration phenomena. [Pg.887]

Differential Scanning Calorimetry has been used for studying the interaction of labdanes 1 (labd-13(E)-ene-8o,15-dio1), 2 (labd- 3(E)-cne-8u-ol-15-yl-acetate) and 3 (labd-14-ene-8,13-diol (Sclareol)) Fig. (12) [76-77] with DPPC model lipid bilayers. The thermotropic changes caused by the labdanes in DPPC bilayers could be used for evaluating the incorporation efficiency of labdanes in DPPC liposomes. Furthermore in these studies [29, 76], a comparison with die structurally similar molecule to cholesterol was carried out based on their thermotropic behavior. The development of liposomal formulations incorporating 1 and 2 has been achieved, while the stability studies of the liposomal formulations based on -potential and on liposomal size have been evaluated. [Pg.200]


See other pages where Differential scanning calorimetry in the study of lipid structures is mentioned: [Pg.87]    [Pg.47]    [Pg.276]    [Pg.96]    [Pg.105]    [Pg.221]    [Pg.448]    [Pg.211]    [Pg.126]    [Pg.352]    [Pg.191]    [Pg.617]    [Pg.191]    [Pg.198]    [Pg.220]    [Pg.489]    [Pg.62]    [Pg.243]    [Pg.11]   


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