Diethyleneglycol-dimethylether

CH3)jAsC H,As(CH3)j diethylenetriamine, [HjN(CH3)3]3NH diethyleneglycol dimethylether, CH30(CHjCH30)3CH3 dilute... 

CH,),AsqH As(CH3), diethylenetriamine, [HjNCCHpj NH diethyleneglycol dimethylether, GHjOtCH CH O GHj dilute... 

A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethyleneglycol dimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3-ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C. 

The corresponding hexachloroceric acid has been isolated in the form of its adduct with diglyme (diglyme = diethyleneglycol dimethylether) by treatment of hydrated ceria with thionyl chloride in the presence of diglyme according to Scheme 5. 

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