Dideoxynucleotide sequencing technique

One sequencing technique is the Sanger method (developed by Fred Sanger) which uses dideoxynucleotides that stop chain elongation at the site of their incorporation. The four dideoxynucleotide substrates are labeled with... 

Yet nucleic acids do it relatively quickly and with amazing precision. Indeed this reannealing (or hybridization) capability between a polynucleotide and a complementary piece of oligonucleotide (commonly called a printer or a probe) forms the basis of such diverse and critical techniques as dideoxynucleotide sequencing, site-specific mutagenesis, cDNA cloning, and hybridization screening of recombinant DNA clones. Nucleic acid hybridization also serves as the basis... 

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