1,1-dichloro-l-fluoroethane

Lin, S. H. and Chen, Y. V., Adsorption and desorption characteristics of 1,1-dichloro-l-fluoroethane by granular activated carbon and activated carbon fiber, J. Environ. Sci. Health, Part A Toxic / Hazard Subst. Environ. Eng., 1996,31(6), 1279 1292. 

This report is the second volume in the series Acute Exposure Guideline Levels for Selected Airborne Chemicals. AEGL reports for aniline, arsine, monomethylhydrazine, and dimethylhydrazine were reviewed in the first volume. AEGL documents for five chemicals—phosgene, propylene glycol dinitrate, 1,1,1,2-tetrafluoroethane, 1,1-dichloro-l-fluoroethane, and hydrogen cyanide—are published as an appendix to this report. The subcommittee... 

Dichloro-l-fluoroethane (HCFC-141b)i Acute Exposure Guideline Levels... 

Hydrochlorofluorocarbon-141b, or 1,1-dichloro-l-fluoroethane (HCFC141b), has been developed as a replacement for fully halogenated chlorofluorocarbons because its residence time in the atmosphere is shorter, and its ozone depleting potential is lower than that of presently used chlorofluoro... 

AIHA (American Industrial Hygiene Association). 1998. Environmental Exposure Level Guide 1,1-dichloro-l-fluoroethane. Fairfax, VA. 

Aster, A. and F.Paraire. 1997. Fatal intoxication with 1,1-dichloro-l-fluoroethane. N. Engl. J. Med. 337 940. 

Brock, W.J., H.J.Trochimowicz, R.J.Millischer, C.Farr, T.Kawano, and G.M. Rusch. 1995. Acute and subchronic toxicity of 1,1-dichloro-l-fluoroethane (HCFC-141b). Fd. Chem. Toxicol. 33 483 190. 

ECETOC (European Centre for Ecotoxicology and Toxicology of Chemicals). 1994. Joint assessment of commodity chemicals no. 29 1,1-dichloro-l-fluoroethane (HCFC-141b) CAS No 1717-00-6. ECETOC, 4 Avenue E. Van nieuwenhuyse (Bte 6) 1160—Brussels, Belgium. 

Tong, Z., M.J.Utell, P.E.Morrow, G.M.Rusch, M.W.Anders. 1998. Metabolism of 1,1-dichloro-l-fluoroethane (HCFC-141b) inhuman volunteers. Drug Metab. Disp. 26 711—713. 

DERIVATION SUMMARY FOR ACUTE EXPOSURE GUIDELINE LEVELS FOR 1,1-DICHLORO-l-FLUOROETHANE (HCFC-141b) (CAS No. 1717-00-6)... 

Simmonds, P. G., S. O Doherty, J. Huang, R. Prinn, R. G. Derwent, D. Ryall, G. Nickless, and D. Cunnold, Calculated Trends and the Atmospheric Abundance of l,l,L2-Tetrafluoroethane, 1,1-Dichloro-l-fluoroethane, and l-Chloro-l,l-difluoroethane Using Automated in Situ Gas Chromatography-Mass Spectrometry Measurements Recorded at Mace Head, Ireland, from October 1994 to March 1997, J. Geophys. Res., 103, 16029-16037 (1998b). 

Chlorofluorocarbon (CFC) replacements have recently been used for their lower stability and because they have carbon-hydrogen bonds, which means that their atmospheric lifetime is expected to be much shorter than those of CFCs. The adsorption properties of l,l,2-trichloro-l,2,2-trifluoroethane (CFC 113) and its replacement compounds, l,l-dichloro-2,2,2-trifluoroethane (HCFC123), 1,1-dichloro-l-fluoroethane (HCFC141b), and l,l-dichloro-l,2,2,3,3-pentafluoropropane (HCFC225ca) on four kinds of activated carbons were investigated. The adsorption isotherms of inhalational anesthetics (halothane, chloroform, enflurane, isoflurane, and methoxyflurane) on the activated carbon were measured to evaluate the action mechanism of inhalational anesthesia. The anesthesia of CFC replacements can be estimated by the Freundlich constant N of the adsorption isotherms (Tanada et al., 1997). 

HCFCs are viable substitutes for CFCs, but they can have catastrophic effects on some polymeric substrates, owing to increased polarity and solvent strength. To reduce or eliminate substrate attack, PFCs can be combined widi HCFCs. PFCs are miscible with most HCFCs, such as HCFC-141b (1,1-dichloro-l-fluoroethane) and HCFC-225 (pentafluorodichloropropane) and therefore can be mixed in any proportion to obtain the desired inerting behavior. 

Chlorine can be substituted by hydrogen fluoride and boron trifluoride to yield chlorofluorocarbon compounds. This process is applied for producing 1,1-dichloro-l-fluoroethane (14), which is considered as a replacement for trichlorofluoromethane as a blowing agent for plastic foam.18... 

Dichloro-l-fluoroethane, 0734 (2,2-Dichloro-1 -fluorovinyl)ferrocene, 3463 N,N-Dich IorogIycine, 0735... 

Maezawa, Y., Sato, H., Watanabe, K. (1991b) Liquid densities and vapor pressures of 1,1,2,2-tetrafluoroethane (HFC 134) and 1,1-dichloro-l-fluoroethane (HCFC 141b). J. Chem. Eng. Data 36, 151-155. 

Hydrochlorofluorocarbons (HCFCs) are now being produced in very large quantities as substitutes for ozone-depleting chlorofluorocarbons (CFCs). The two most common HCFCs are 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123) and 1,1-dichloro-l-fluoroethane (HCFC-141b) ... 

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