3.4- Dichloro-5-isopropoxy-2

A. 3,4-Dichloro-5-isopropoxy-2(5H)-furanone.2 A 1-L, round-bottomed flask equipped with a Dean-Stark trap, condenser, argon bubbler, and magnetic stirrer is charged with 50.7 g (0.30 mol) of mucochioric acid (Note 1), 46 mL (0.60 mol) of isopropyl alcohol, 300 mL of toluene, and 20 drops of coned sulfuric acid. The mixture is heated to reflux with stirring overnight (-18 hr) with separation of water. The... 

B. 7-Chloro-7-cyanobicyclo[4.2.0]octan-8-one. To a 250-mL Erlenmeyer flask is added 20.0 g (94.8 mmol) of 3,4-dichloro-5-isopropoxy-2(5H)-furanone and 120 mL of methanol. The flask is cooled in an ice bath with stirring and 7.5 g (115.4 mmol) of sodium azide is added. The ice bath is removed after 15 min and the mixture is stirred for an additional 50 min. After dilution with 600 mL of water, the reaction mixture is extracted with one 100-mL and two 50-mL portions of toluene. The combined organic layers are washed with water (2 x 100 mL) and with 100 mL of brine and are dried with magnesium sulfate. TLC analysis (1 1 ethenhexane, S1O2) indicates only one component (Rf = 0.38) and no remaining dichlorofuranone (Rf = 0.45) (Note 3). 

Dichloro-5-isopropoxy-2(5H)-furanone 2(5H)-Furanone. 3,4-dichloro-5-isopropoxy- (8) 2(5H)-Furanone, 3,4-dichloro-5-(1-methylethoxy)- (9) (29814-12-8) Mucochloric acid Malealdehydic acid, dichloro- (8) 2-Butenoic acid, 2,3-dictiloro-4-oxo-, (2)- (9) (87-56-9)... 

Dichloro 4 iodo phenol iodofenphos Dichloro isopropoxy phenyl hydrazine oxadiazon Dichloro maleic anhydride fluoramide... 

Dichloro-phenyl)-1 -[2-(3-isopropoxy-phenyl)-acetyl]-piperidin-3-yl -ethyl)-4-phenyl-1-azonia-bicyclo[2.2.2]octane chloride, C37H45CI3N2O2,... 

Angeletakis [2] prepared metathesis-curable dental compositions using 1,3-bis-(2,4,6-trimethylphenyl)-2-(imidazolidinylideii ) dichloro(o-isopropoxy-... 

As noted in Section 5.2.2.1.2.3., the reaction of 1,1-dichlorocyclopropanes with alkoxides does not give the ordinary alkenyl(alkylidene)cyclopropane products when the side chains of the substrate cannot accommodate the double bonds in these positions. Instead, the usual course of the reaction in these cases is double elimination followed by addition of alkoxide to the cyclopropene double bond. Thus, c -l,l-dichloro-2,3-dimethylcyclopropane (1), when treated with potassium isopropoxide in dimethyl sulfoxide at 30 °C, gave a mixture of two isomeric ethers, l-isopropoxy-l-methyl-2-methylenecyclopropane (2) and tra 5-l-isopropoxy-2-methyl-3-methylenecyclopropane (3), in 31% and 35% yield, respectively. When 1 was reacted with potassium rcrt-butoxide in the presence of sodium methoxide the corresponding methyl ethers 4 and 5 were obtained in yields of 35% and 17%. ... 

CloH2oCl202Pt, DichlorO bis[methyl(isopropoxy)carbene]-platinum,... 

---