1.1- dichloro-3,5-dioxo-2-ethyl

A solution of 27.6 g (0.16 mol) of freshly distilled ethyl 7-aminoheptanoate in 40 ml of nitro-methane was added all at once and with mechanical stirring to a suspension of 26.2 g (0.08 mol) of 5,8-dichloro-10-dioxo-11 -methyldibenzo[c,f] thiazepined, 2) in 1 20 ml of nitro-methane. The whole was heated to 55°C for 30 minutes, the solvent was then evaporated in vacuo and the residue was taken up in water. The crude ester was extracted with ether. After evaporation of the ether 36 g of crude ester were obtained, and 30 g (0.065 mol) thereof were treated under reflux with a solution of 2.8 g (0.07 mol) of sodium hydroxide in 75 ml of eth-... 

Dichloro-2,6-dimethyl-3,5-dioxo-4-ethyl- E12b, 536 (R-CH2-CO-A-CO-CH2-R + TeCl4)... 

---