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Dibenzocyclooctadiene derivatives

Noapkeaolic oxidative coupiing. The final step in a s)rnthe is of ( )-iso-stegnane, (2), a dibenzocyclooctadiene derivative, involved oxidative coupling of(l).=... [Pg.461]

TABLE 9-7. Anti-HIV Activities of Potent Dibenzocyclooctadiene Lignans and Biphenyl Derivatives ... [Pg.376]

Dibromination of Dibenzocyclooctadiene Lignans Five dibrominated derivatives (142-146, Figure 9-8) were synthesized from compounds 132 and 137-140, and evaluated for anti-HIV activity. Only 143 had an ECso lower than 10 pM (EC50 = 7.2 pM and TI = 5) however, it was still less potent than its parent compound 137 (EC50 = 2.0 pM and TI = 56, Table 9-7). [Pg.376]

Treatment of the 3,4-dibenzyltetrahydrofuran (203), derived by cyclisation of dihydrocubebin, with DDQ in acetic acid causes dehydrogenation to the aryltetralin (204), presumeably via the acetoxy compound (205), which is obtained as a second product from the reaction. However the same reaction carried out in TFA affords the dibenzocyclooctadiene (206) (scheme 75) [157]. [Pg.785]


See other pages where Dibenzocyclooctadiene derivatives is mentioned: [Pg.189]    [Pg.775]    [Pg.777]    [Pg.779]    [Pg.790]    [Pg.189]    [Pg.775]    [Pg.777]    [Pg.779]    [Pg.790]    [Pg.57]    [Pg.376]    [Pg.378]    [Pg.391]    [Pg.543]   
See also in sourсe #XX -- [ Pg.24 , Pg.775 , Pg.776 , Pg.777 , Pg.778 , Pg.779 , Pg.780 ]




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