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Diazirines trifluoromethyl

Chen, F.-Q., et al. (1994). Synthesis and preliminary chemi- and bioluminescence studies of a novel photolabile coelenterazine analogue with a trifluoromethyl diazirine group. Chem. Commun. 2405-2406. [Pg.386]

As was mentioned above, bis(trifluoromethyl)carbene [30] was not detected in matrix IR spectra of the products formed upon vacuum pyrolysis (500-1000°C, 10 Torr) of diazirine [29] or perfluoropropylene. [Pg.17]

Singlet halo(trifluoromethyl)carbenes [33a]-[33c], which were characterized by IR and UV spectroscopies and chemical trapping with HCl, have been generated from respective 3-halo-3-(trifluoromethyl)diazirines [34a]-[34c] frozen in an argon matrix at 12 K and irradiated with UV light at... [Pg.17]

Some diazirines, particularly the 3-trifluoromethyl-3-aryldiazirines, can rearrange upon photolysis to a linear diazo derivative, similar in structure to the photosensitive end of the crosslinker PNP-DTP (Chapter 5, Section 3.12). These isomerized products themselves can be photolyzed to the reactive carbene. [Pg.208]

The absolute rate constants for reaction of /t-tolyl(trifluoromethyl)carbene, generated by laser flash photolysis of the corresponding diazirine, with pyridine (4 x lO lmor s ... [Pg.254]

Trifluoromethyl)-3//-diazirin-3-yl]arenes, e.g. 36 (R1 = CF3), were introduced as photophores by Brunner et alJ116 to provide a more favorable carbene than the one produced from diazoesters[117 or from aryldiazirines. 118 Both 3//-diazirin-3-ylarenes I8-1201 and the [(3-tri-fluoromethyl)-3//-diazirin-3-yl]arenes (e.g., 36, R = H, CF3, respectively) 116 are more stable in acid than most diazoesters, and photolyze at around 360 nm to generate highly reactive carbenes such as 37. However, these diazirines can photo-isomerize to some extent to the... [Pg.105]

Scheme 11 Photolysis Reactions of [3-(Trifluoromethyl)-3//-diazirin-3-yl]arenes and 3/f-Diazirin-3-ylarenes171... Scheme 11 Photolysis Reactions of [3-(Trifluoromethyl)-3//-diazirin-3-yl]arenes and 3/f-Diazirin-3-ylarenes171...
The synthesis reported by Nassal is based on the Ca-alkylation of diethyl 2-(ace-tylamino)malonate by 3-[4-(bromomethyl)phenyl]-3-(trifluoromethyl)-3//-diazirine (46) (Scheme 12) J122l The precursor for the diazirine-containing alkylating agent is 2,2,2-trifluoro-l-(4-tolyl)ethanone (39).1124 ... [Pg.106]

Scheme 13 Synthesis of 4-[3-(Trifluoromethyl)-3/f-diazirin-3-yl]-D,L-phenylalanine According to Shih and Bayley[125l... Scheme 13 Synthesis of 4-[3-(Trifluoromethyl)-3/f-diazirin-3-yl]-D,L-phenylalanine According to Shih and Bayley[125l...
Acetylamino)-2- 4-[3-(trifluoromethyl)-3//-diazirin-3-yllbenzyl)inalonic Acid (48) [122)... [Pg.110]

The syntheses of 4-[3-(trifluoromethyl)-3//-diazirin-3-yl]arene-containing peptides are carried out in a straightforward manner. In solid-phase syntheses, H-Phe(4-Tmd)-OH [Tmd = 3-(trifluoromethyl)-3//-diazirin-3-yl] is incorporated as the Fmoc-Phe(4-Tmd)-OH (Table 4).[i23,130-133] Solution-phase syntheses of [Phe4(4-Tmd)J-Leu-enkephalin and [Phe2(4-Tmd)J-aspartame employ Boc-Phe(4-Tmd)-OH and are carried out by the mixed anhydride method.1122 Apparently Phe(4-Tmd) is stable in TFA/CH2C12 (1 1) for 30 min at rt 122 or even in neat TFA for 15 min at 0°CJ134] A post-synthetic modification of a free peptide has been carried out by the mixed anhydride mediated coupling of 4-[3-(trifluoromethyl)-3/7-diazirin-... [Pg.112]

Diazido-1,2,4,5-tetrazine, 1013b Diazido(trifluoromethyl)arsine, 0306 Diazirine, 0404... [Pg.2073]

Diazirine-3,3-dicarboxylic acid, 1077 Difluorodiazirine, 0341 Dipotassium diazirine-3,3-dicarboxylate, 1336 3-Fluoro-3-(trifluoromethyl)-3/7-diazirine, 0627 3-Methyldiazirine, 0804 3,3-Pentamethylenediazirine, 2416 Potassium hydrogen diazirine-3,3-dicarboxylate, 1065 3-Propyldiazirine, 1589... [Pg.2298]

Trifluoromethyl Imines, Oximes, Hydrazones, Imidoyl Chlorides, Nitrones, Diazo and Diazirine Compounds... [Pg.204]

See other pages where Diazirines trifluoromethyl is mentioned: [Pg.16]    [Pg.190]    [Pg.609]    [Pg.105]    [Pg.106]    [Pg.109]    [Pg.109]    [Pg.110]    [Pg.110]    [Pg.110]    [Pg.111]    [Pg.112]    [Pg.112]    [Pg.112]    [Pg.112]    [Pg.112]    [Pg.113]    [Pg.113]    [Pg.114]    [Pg.116]    [Pg.65]    [Pg.273]    [Pg.2094]    [Pg.2374]   
See also in sourсe #XX -- [ Pg.205 ]



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3-trifluoromethyl-3- diazirine

Diazirin

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Diazirines

Diazirines 3-trifluoromethyl-3-aryl

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