Diazaspiro decane

Chemical Name 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.51 decan-2-one Common Name Decaspiride... 

Synthesis of 2-ethyl-8[11C]methyl 2,8-diazaspiro[4f5]decane-1,3-dione ([11C]RS 86)... 

An interesting study reported in 2001, although it did not utilize any inverse-detected 2D NMR data, did report a wealth of useful chemical shift data for parent azoles and benzazoles. Solid-state chemical shift data were reported for several pyrazole analogues by Alvarez-Larena. Trofimenko et al reported a study of the buttressing effects of the A-tert-h xiy group of a series of pyrazoles in the solid state, followed by a study by Claramunt and co-workers of a series of halo triazoles. Martins and co-workers reported data for a series of 5-trichloromethyl-1,2-dimethyl-1/f-pyrazolium chlorides. Malpass and co-workers reported direct observe chemical shift data for a series of bicyclic amines and lactams. Recently, a large body of chemical shift data for a series of l,4-diazaspiro[4.5]decanes and l,4-oxazaspiro[4.5]-decanes using direct observe methods were reported by Ariza-Castolo and co-workers. " Readers with an interest in the chemical shift behavior of these systems are directed to these references as a source of data. 

The reaction of propane-1,3-diamine with phthalic anhydride gives the pyrimidoisoindolone (415), some of whose reactions were investigated Syntheses of the l,8-diazaspiro[4,5]decane (416) and l-oxa-8-azaspiro-decane (417) systems have been reported. ... 

Bipyirolidine]-2,2 -dione, B-70125 Cyclo(prolylalanyl), C-80194 > l,3-Diazaspiro[4.5]decane-2,4-dione, D-60056... 

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