Diastereoselective Alkylation of Glycine Schiff Base with Optically Enriched Alkyl Halides

3 Diastereoselective Alkylation of Glycine Schiff Base with Optically Enriched Alkyl Halides 

Despite numerous efforts to develop the asymmetric phase-transfer-catalyzed alkylation of 2 into a powerful method for the synthesis of natural and unnatural a-amino adds, the stereochemistry of the alkylation of 2 with chiral electrophiles has scarcely been addressed. 

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