Diamines alkyl derivatives

Sulfur Bake. The yellow, orange, and brown sulfur dyes belong to this group. The dyes are usually made from aromatic amines, diamines, and their acyl and nuclear alkyl derivatives. These may be used in admixture with nitroanilines and nitrophenols or aminophenols to give the desired shade. The color formed is said to be the result of the formation of the thiazole chromophore, evident in dye structure (1). 

Alkylation of amines usually proceeds more slowly than acylations, and alkylating reagents can usually be thoroughly mixed with an amine before reaction is complete. Diamines or polyamines can therefore be transformed into mixtures of the statistically expected amounts of alkylated derivatives (Scheme 10.17). The use of CsOH as base has been found to be particularly conducive to the formation of monoalkylated products [72]. Some polyamines have also been monoalkylated selectively after complexation with Zn(II) [73],... 

Utility. Many asymmetric syntheses have been developed using vicinal diamines as the source of chirality. The major interest lies in their use as precursors for the synthesis of a broad family of bidentate ligands. Many reactions have also been described using the N-alkyl derivatives of these diamines as chiral auxiliaries and protecting groups of aldehydes. Most of these applications generally use the framework of l,2-diphenyl-l,2-diaminoethane (7) or 1,2-diaminocyclohexane (8), whose preparations have been fully described. ... 

Several iV, iV -alkylaled derivatives of purine-2,6-diamine have been prepared by the stepwise reaction of aliphatic amines with 2,6-dichloropurine, e.g. formation of 16."... 

Ar= Ph and alkyl derivatives, o-Ph, p-Ph, p-PhCO, p-PhCH=CHCgH4, 1-naphthyl, p-N02Me4Cg, m-N02Me4Cg (giving diamines) (ref. 20)... 

In the absence of mineral acids the condensation of alloxane with pyridine-2,3-diamines in aqueous solution yields yellow 3-oxo-3,4-dihydropyrido[2,3-h]pyrazine-2-carboxyureide (26 R = H) or 4-alkyl derivatives, together with small amounts of the corresponding 2-oxo-l,2-di-hydropyrido[2,3-h]pyrazine-3-carboxyureide.23 27 28... 

By far the most common approach to the 1,3-diazocine ring system has been and remains dependent on formation of the aminal functionality through condensation of appropriate one-carbon sources with diamines. Alkylation of a,(u-disulfonamides with methylene bromide affords modest yields (ca. 45%) of perhydrodiazocine derivatives (5 Ar=p-tolyl, phenyl) (Equation (7))... 

CAS 61790-85-0 (generic) 90367-27-4 EINECS/ELINCS 291-275-8 Synonyms Ethanol, 2,2 -((3-((2-hydroxyethyl) amino) propyl) imino) bis-, N-tallow alkyl derivs. PEG-3 N-tallow-1,3-diaminopropane PEG-3 tallow propylene diamine POE (3) tallow aminopropylamine N-Tallow alkyl 2,2 -[[3-[(2-hydroxyethyl) amino] propyl] imino] bisethanol Classification Ethoxylated diamine... 

Benaglia and coworkers have developed a number of chiral ligands based on binaphthyl diamine (190) for CuOTf-catalyzed additions of terminal alkynes to preformed imines (Scheme 17.39) [51]. In a screen of the parent binaphthyl diamine (190) and N-alkylated derivatives, ligand (190) was found to provide moderate enantioselectivity in the addition of phenylacetylene (189) to imine (188). The selectivity could be improved by using bis-imine derivative (191) as the chiral ligand in the reaction [52]. 

Almost all IDA derived chain extenders are made through ortho-alkylation. Diethyltoluenediamine (DE I DA) (C H gN2) (53), with a market of about 33,000 t, is the most common. Many uses for /-B I DA have been cited (1,12). Both DE I DA and /-B I DA are especially useful in RIM appHcations (49,53—55). Di(methylthio)-TDA, made by dithioalkylation of TDA, is used in cast urethanes and with other TDI prepolymers (56). Styrenic alkylation products of TDA are said to be useful, eg, as in the formation of novel polyurethane—polyurea polymers (57,58). Progress in understanding aromatic diamine stmcture—activity relationships for polyurethane chain extenders should allow progress in developing new materials (59). Chlorinated IDA is used in polyurethane—polyurea polymers of low hysteresis (48) and in reinforced polyurethane tires (60). The chloro-TDA is made by hydrolysis of chloro-TDI, derived from TDA (61). 

In addition to the mono- and dialkylamines, representative stmctures of this class of surfactants include /V-alkyltrimethylene diamine, RNH(CH2)3NH2, where the alkyl group is derived from coconut, tallow, and soybean oils or is 9-octadecenyl, 2-aLkyl-2-imidazoline (3), where R is heptadecyl, heptadecenyl, or mixed alkyl, and l-(2-aniinoethyl)-2-aLk5l-2-imidazoline (4), where R is heptadecyl, 8-heptadecenyl, or mixed alkyl. 

Alkylation of the tetrahydropyridine, 52 (obtained by reaction of a suitable protected derivative of 4-piperidone followed by dehydration and deprotection), with chloroacetonitrile affords 53, Reduction of the cyano group gives the diamine (54). Reaction of this intermediate with the S-methyl ether of thiourea affords guancycline (55). 

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