Diabetes mellitus niacin supplementation

The European Health Food Manufacturers Federation restricts over-the-counter supplements to 500 mg per day (Shrimpton, 1997). Where niacin is being used to treat clinically significant hyperlipidemia, and in trials for the prevention of type I diabetes mellitus, a tentative upper limit has been set at 3 g per day (Knip et al., 2000). 

Niacin is a nutritional supplement used during periods of deficiency known as pellagra and for the treatment of dyslipidemia. Niacin needs may increase during chronic illness such as diabetes mellitus, malignancy, metabolic diseases, hyperthyroidism, infections, chronic fever, alcoholism, and during pregnancy and lactation. 

---