Development, drug, team members

In this scenario, QA interacts with team members during the drug development process and reports observations to team members for their corrective and preventative action and documentation process. 

The nursing process is a framework for nursing action consisting of problem-solving steps that help members of the health care team provide effective patient care. It is both a specific and orderly plan used to identify patient problems, develop and implement a plan of action, and then evaluate the results of nursing activities, including the administration of drug . 

If it is possible to measure the T1/2 of the drug in question during the period that the patient is hooked up to the dialysis machine, to estimate the Vj for that substance (and the existing intrinsic clearance has been measured during the non-dialysis period - from a similar exercise of repeated plasma concentration measurement), then it is possible to work out how much drug is being lost through the dialysis process itself. Even in the more sophisticated centres of the developed world this would be a heroic exercise and would seldom be done unless a fervent pharmacoki-neticist was a member of the ward team. 

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