Deuterating Agents

D) exchange reactions, which are important for producing labeled compounds for kinetic and metabolic studies in the pharmaceutical industries [44]. While we do not know of any real world applicahons, it has been shown that both selective as well as extensive deuteration are possible, depending on the Ir catalyst and the deuterating agent. 

The deuterating agent is a probe of the accessibility of the materials to small polar molecules. The FTIR spectra of chitosan aerogel submitted to increasing pressures of D2O are reported in Fig.l2. The admission of D2O vapor brings about a progressive decrease of the intensity of all O-H and N-H bands. At a D2O pressure of 13 mbar, the O-H and N-H bands have virtually disappeared. 

Gas-Phase Acidity and Basicity of Common Deuterating Agents... 

Reaction times typically range from milliseconds to 10 s, although exchange times up to 40 s have been accomplished [13]. Furthermore, when a pulsed deuterating agent introduction system is not used, the actual reaction time is approximately the sum of the ion accumulation time, any isolation time, and any exchange time, since the deuterating... 

In conclusion, it may be appropriate to emphasize the importance of Reaction (1) as a pathway for deuterating interstellar molecules. It synthesizes in a single step deuterated species of the same complexity as the starting material and, as the deuterating agent, it uses deuterium atoms, the primary source of deuterium. Thus it would pear to provide possible routes for the synthesis of CCD via CoHp+ + D - CpHD+ + H and for the synthesis of CoHD via CoH+ +... 

---