Detoxication hydrogen peroxide

Figure 6.10 Production of various reactive oxygen species, the role in tissue damage, and their detoxication and toxication. Reactive species shown are hydrogen peroxide, superoxide, and hydroxyl radical.

The detoxication of hydrogen peroxide with glutathione peroxidase is as follows ... 

These are small vesicles which are present in almost all eukaryotic cells. They contain a variety of oxidative enzymes and are a major site of O2 utilization. Although hydrogen peroxide is produced, this is prevented from accumulating because catalase is present. Peroxisomes are believed to play an important part in detoxication reactions in the liver and kidney, e.g. in the conversion of alcohol to acetaldehyde. 

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