Detection at Gold Amalgam Electrodes

HPLC ofcaptopril in plasma and urine (re-drawn from Perrett and Drury ). Column 5 m Hypersil ODS Eluent pH 2, 100 mmol L potassium dihydrogen orthophosphate Flow-rate I mL min Detection Hg/Au electrode, - -0.05 V vs Ag/AgCl A. Patient plasma blank, B. Plasma blank (1 mL) with 25 pmol captopril added, C. Urine from patient 1 h after receiving captopril (6 mg, oral). 

Gold amalgam electrodes have been successfully used with CZE for certain applications. Jin and Wang showed that a gold amalgam electrode used without 

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