Desoxyephedrine

Hydroxydione sodium succinate d-Desoxyephedrine HCI Benzphetamine HCI 11 -Desoxy-17-hydroxycorticosterone Hydrocortisone 3 -Diacetoxyacetophenone Fenoterol hydrobromide Metaproterenol sulfate 3,17-Diacetoxy-5a-androstane-2,16-diene... 

Boranes have opened the door to asymmetric reduction of carbonyl compounds. The first attempt at modifying borane with a chiral ligand was reported by Fiaud and Kagan,75 who used amphetamine borane and desoxyephedrine borane to reduce acetophenone. The ee of the 1-phenyl ethanol obtained was quite low (<5%). A more successful borane-derived reagent, oxazaborolidine, was introduced by Hirao et al.76 in 1981 and was further improved by Itsuno and Corey.77 Today, this system can provide high stereoselectivity in the asymmetric reduction of carbonyl compounds, including alkyl ketones. 

Common Name Desoxyephedrine hydrochloride Metamfetamine hydrochloride Metamphetamine hydrochloride Methaphetamine hydrochloride Methylamphetamine hydrochloride Phenylmethylaminopropane hydrochloride... 

Synonyms. /-Deoxyephedrine Desoxyephedrine Methamphet-amine Phenylmethylaminopropane. 

Grams of the ketimine as produced was dissolved in 45 cc. of ethyl acetate as a solvent. To this was added 10 grams of 5% palladium on charcoal and the mixture reduced by the addition of hydrogen until 1.39 moles of hydrogen was absorbed. The catalyst was removed and the product distilled. Distillation gave the desired desoxyephedrine boiling at 58-61.5° C at 1.1 mm. pressure. 

Methamphetamine Hydrochloride. Methampheta-mine, (-( )-1 -phenyl-2-methyiaminopropane hydrochloride desoxyephedrine hydrochloride (Dcsoxyn). is the N-methyl analogue of dextroamphetamine. It has more marked central and lc.ss peripheral action than dextroamphetamine. It has a very high abuse potential, and by the intravenous route, its sails are known as .speed." The overall abu.se problem presented by the drug is a national disaster. Medicinally acceptable u.scs of methamphetamine are analogous to tliose of dextroamphetamine. 

METHAMPHETAMINE HYDROCHLORIDE (DESOXYEPHEDRINE HYDROCHLORIDE) (Desoxyn tablets 5 mg)... 

The use of optically active borane reagents for asymmetric reductions was first reported by Fiaud and Kagan in 1969.2 These workers used the desoxyephedrine-boron complex 2 as a... 

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