Desoxy cholic acid

An additional 5-7 g. of product may be obtained by concentrating the filtrate and recrystallizing the product from acetone. If the material is to be used for the preparation of wor-desoxy cholic acid (p. 38), it is more convenient to oxidize the filtrate directly with chromic acid and isolate the product as the acid. 

The two most important bile acids, cholic acid C24H40Os and desoxy-cholic acid C24H40O4, occur in ox bile in combination, partly with glycine and partly with taurine as glyco- and taurocholic and glyco- and tauro-desoxycholic acids. The linkage between the amino acids and the bile acids is of an amide nature. On hydrolysis the nitrogenous constituents are split off. 

OX BILE, Fel taurisOn bile is obtained from cattle in slaughterhouses, and contains sodium salts of some 20 conjugated bile acids. Among these, cholic acid and desoxy-cholic acid occur in the ratio 10 1. 

Prepn from coprostane, cholic acid, lithocholic acid, desoxy-and chenodesoxycholic acid Wieland, Weil, Z. Physio/. 

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