Dermatan sulfate carbohydrate chains

These studies of neural development not only emphasize the importance of chondroitin/dermatan sulfate glycosaminoglycan chains, but also illustrate the utility of carbohydrate-specific monoclonal antibodies in studies of development and aging. In recent years a large number of monoclonal antibodies have been developed which recognize carbohydrate epitopes associated with chondroitin and dermatan sulfate glycosaminoglycan chains [3, 7, 20, 43, 62, 64, 70]. Many of these... 

In dermatan sulfate from shark skin, there is about a 40% excess of sulfate groups over 2-acetamido-2-deoxy-D-galactose residues.300 The small proportions of D-glucu-ronic acid (d-GUA) present in dermatan sulfate occur in regions of the carbohydrate chains both near to, and far from, the carbohydrate-peptide linkage region. The isolation of the tetrasaccharide... 

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