Derivatives in Urine

It has been possible to detect indole derivatives in urine through TLC of 50—100 [xl of the untreated samples [12]. Ether- or ethyl acetate- 

---

Tedeschi L, Frison G, Castagna F, Giorgetti R, Ferrara SD. 1993. Simultaneous identification of amphetamine and its derivatives in urine using HPLC-UV. Int J Legal Med 105... 

Geiser, L., Cherkaoui, S., and Veuthey, J. L. (2000). Simultaneous analysis of some amphetamine derivatives in urine by nonaqueous capillary electrophoresis coupled to electrospray ionization mass spectrometry./. Chromatogr. A 895, 111 — 121. 

S. Myung, S. Yoon and M. Kim, Analysis of benzene ethylamine derivatives in urine using the programmable dynamic liquid-phase microextraction (LPME) device. Analyst, 2003,128(12), 1443-1446. 

Folin, O., and Denis, W., 1915, A colorimetric method for the determination of phenols (and phenol derivatives) in urine, J. Biol. Chem. 22 305-308. 

McCooeye, M. A., Mester, Z., Ells, B., Barnett, D. A., Purves, R. W., and Guevremont, R. (2002). Quantitation of amphetamine, methamphetamine, and their methylenedioxy derivatives in urine by solid-phase microextraction coupled with electrospray ionization-high-field asymmetric waveform ion mobility spectrometry-mass spectrometry. Anal. Chem. 74 3071-3075. 

Concentration of the drug on adsorbent columns has been done for the analysis of theophylline and its metabolites in urine15 and for some other xanthine derivatives in urine and... 

McCooeye, M.A. Mester, Z. Ells, B. Barnett, D.A. Purves, R.W. Guevremont, R. Quantitation of Amphetamine, Methamphetamine, and Their Methylene-dioxy Derivatives in Urine by Solid-Phase Microextraction Coupled with Electrospray lonization-High-Field Asymmetric Waveform Ion Mobility Spectrometry-Mass Spectrometry, Anal. Chem. 74, 3071-3075 (2002). 

Trippel-Schulte, P., Zeiske, J., and Kettrup, A., Trace analysis of selected benzine and diamino diphenyl methane derivatives in urine by means of liquid chromatography using precolumn sample preconcentration, UV and electrochemical detection, Chromatographia, 22, 138-146, 1986. 

The problems of benzodiazepine abuse have been known about for a long time. Nevertheless, the extent of the abuse of these substances and the consequences of their pharmacodynamic interactions with other drugs and medicaments are often underestimated. Consequently, the problems of determining these substances and their derivatives in urine accurately and with good sensitivity are not appreciated to an equal extent by all analysts or by all who submit samples to them. 

Table 8-18, Cut-off values of some phencyclidine derivatives in urine...

Wei, R, Fan, Y., Zhang, M., and Feng, Y.-Q., Poly(methacrylic acid-ethylene glycol dimethacrylate) monolith in-tube solid-phase microextraction applied to simultaneous analysis of some amphetamine derivatives in urine by capillary zone electrophoresis, Electrophoresis, 26, 3141, 2005. 

VON Euler, Chr., von Euler, U.S. and Floding, I., Biologically inactive catechol derivatives in urine, Acta physiol, scand. 33, Suppl. 118, 32 (1955). 

The presence of indole and skatole derivatives in urine and fecal contents has long been known. It was demonstrated by Hopkins and Cole that indole was formed from tryptophan by E. coli. 

Derivatives in Urine with Solid Phase Micro-extraction (SPME)." ACTA Pharmaceutica Hungarica 68 (1998), 269-275. 

---