Deoxyribonucleic acid definition

CAS 9007-49-2 EINECS/ELINCS 310-127-6 Synonyms Deoxyribonucleic acid Definition Polynucleotide found in the chromosomes of cell nuclei naturally occurring substance... 

Because of the presence of the cyclic four-membered amide connected to the multicyclic ring systems, an effort to define their mechanism of action would be highly important. Despite a number of synthetic efforts, a relatively small amount of research had been focused on the use of compounds related to PAHs as anticancer agents. Bair et al. [152, 153] reported a close correlation between antitumor activity and the shape of the polyaromatic system. However, his group did not make a definitive correlation between the ability of these compounds to bind to deoxyribonucleic acid (DNA) and their cytotoxic activity. Bair s group developed... 

Deoxyribonucleic acid (DNA) stores the genetic information present in living cells. It allows the cell to make proteins according to a definite sequence of atoms. The DNA molecule consists of two long chains molecules twisted around each other and held together by hydrogen bonds This structure is called a double helix (Fig. 5.20). For this discovery, F. Crick, M. Wilkins and J. Watson gained the Nobel Prize for Medicine in 1962. 

Histones and protamines are present in animal cell nuclei as basic nuclear proteins associated with deoxyribonucleic acid. They are known to be inhomogeneous and probably consist of definite amounts of several components which are very similar in their nature and structure. The significance of the heterogeneity of these basic nuclear proteins has not yet been completely elucidated, though some particular activity in controlling DNA-dependent biosynthesis is sometimes attributed to each component of the histones. 

Deoxyribonucleic Acids as Genetic Material. The substance that makes up the hereditary factors or genes is deoxyribonucleic acid. In general, the current concept is that for each individual gene there is as the chemical equivalent an appropriate DNA characterized by a definite base sequence. The information carried by the gene and finally expressed as a particular character consists in the sequence of the bases. The base sequence in turn determines the primary structure, i.e., the sequence of amino acids, of proteins. There is a direct correlation A certain group of bases of the DNA stands for a certain amino acid in the final protein. 

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