Deoxycholic acid, conjugates structure

Johns WH and Bates TR., Quantification of the binding tendencies of cholestyramine I effect of structure and added electrolytes on the binding of unconjugated and conjugated bile salt anions, /. Pharm. Sci., 58,179-183 (1969). NB These values were quoted from Ekwall P, Rosendahl T and Lofman N, Bile salt solutions. I. The dissociation constants of Bie cholic and deoxycholic acids, Acta Chem. Scand., 11,590-598 (1957). They were measured at concentrations boBi above and below Bie critical micellar concentration range. 

The most prominent BA present in human are cholic acid (C), chenodeoxy-cholic acid (CDC), deoxycholic acid (DC), lithocholic acid (LC), and ursodeoxycholic acid (UDC), as derivatives of 5p-cholan-24-oic acid. Primarily they are present as glycine and taurine conjugates, with the conjugation occurring at carbon 24 of the structure. In addition to the above major BA, a wide array of minor components has been identified. 

Scheme 16 Molecular structures of PEG conjugates containing (a) deoxycholic acid [126], (b) squalene [130], and (c) taxol derivative [131, 132]...

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