Markers deleting

There are three methods of deleting markers in ACID ... 

Hepatocellular carcinoma (HCC) develops in patients with chronic liver diseases associated with hepatitis B and hepatitis C vims infections with high incidences. Here, an acyclic retinoid has been shown to suppress the posttherapeutic recurrence after interferon-y or glycerrhicin treatment in cirrhotic patients who underwent curative treatment of preceding tumors. The retinoid induced the disappearance of serum lectin-reactive a-fetoprotein (AFP-L3), a tumor marker indicating the presence of unrecognizable tumors in the remnant liver, suggesting a deletion of such minute (pre)malignant clones (clonal deletion). As a molecular mechanism of the clonal deletion, a novel mechanism of... 

Buiakova O., Baker H., Scott J., Farbman A., et al. (1996). Olfactory marker protein (OMP) gene deletion causes altered physiological activity of olfactory sensory neurons. Proc Natl Acad Sci 93, 9858-9863. 

Lehmann, D.J., Cortina-Borja, M., Warden, D.R., et al. (2005) Large meta-analysis estab-hshes that ACE insertion-deletion polymorphism as a marker of Alzheimer s disease. Am. J. Epidemiol., 162,305-317. 

Fig. 3 Aquaporin deletion reduces osmotic water permeability in lung, but does not impair active fluid absorption, a AQP expression in epithelia and endothelia in nasopharyngeal cavity, upper and lower airways, and alveoli, b Osmotically driven water transport across the airspace/capillary barrier in perfused lungs from wildtype and indicated AQP null mice. Note the remarkable slowing of osmotic equilibration in mice lacking AQPl or AQP5. c Alveolar fluid clearance measured from the increased concentration of a volume marker 15 min after instillation of isosmolar fluid at 37°C. Where indicated, fluid absorption was inhibited by amiloride or stimulated by isoproterenol. From Bat et al. (1999) and Ma et al. (2000a)...

---