Dehydrogenases dimethylamine dehydrogenase

Yao et al. [53] Wine Alcohol dehydrogenase Carbon paste (NAD+, 7-Dimethylamine-2-methyl-3-... 

Loechel et al. [20] Trimethylamine Fish Trimethylamine dehydrogenase (TMADH) (Dimethylamine) methylene ferrocene (DMAMFe)... 

Trimethylamine dehydrogenase is an iron-sulfur flavoprotein found in the methylotrophic bacterium Methylophilus methylotrophus W3A1. It catalyzes the oxidative N-demethylation of trimethylamine by water with formation of dimethylamine and formaldehyde (Steenkamp and Mallinson, 1976). The protein is a symmetrical dimer consisting of 166kDa subunits (Kasprzak et al., 1983 Lim et al., 1982). Each subunit contains one 4Fe-4S center and one FMN cofactor. The latter is bound covalently through the 6... 

Meiberg, J. B. M., and Harder, W., 1979, Dimethylamine dehydrogenase from Hyphomicro-bium X purification and properties of a new enzyme that oxidizes secondary amines, J. Gen. Microbiol. 115 49958. 

Steenkamp, D. J., and Beinert, H., 1982b, Mechanistic studies on the dehydrogenases of methylotrophic bacteria. 2. Kinetic studies on the intramolecular electron transfer in trimethylamine and dimethylamine dehydrogenase, Biochem. J. 207 2419252. 

Yang, C. C., Packman, L. C., and Scrutton, N. S., 1995, The primary shncture of Hyphomicro-bium X dimethylamine dehydrogenase. Relationship to trimethylamine dehydrogenase and implications for substrate recognition, Eur. J. Biochem. 232 264n71. 

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